Asthma remission: what is it and how can it be achieved?

D Thomas, VM McDonald, ID Pavord… - European …, 2022 - publications.ersnet.org
Asthma treatment goals currently focus on symptom and exacerbation control rather than
remission. Remission is not identical to cure, but is a step closer. This review considers the …

Oxidative stress and inflammation in acute and chronic lung injuries

FS Bezerra, M Lanzetti, RT Nesi, AC Nagato, CP Silva… - Antioxidants, 2023 - mdpi.com
Acute and chronic lung injuries are among the leading causes of mortality worldwide. Lung
injury can affect several components of the respiratory system, including the airways …

[HTML][HTML] Overuse of short-acting β2-agonists in asthma is associated with increased risk of exacerbation and mortality: a nationwide cohort study of the global SABINA …

BI Nwaru, M Ekström, P Hasvold… - European …, 2020 - publications.ersnet.org
Background Overuse of short-acting β 2-agonists (SABA) may indicate poor asthma control
and adverse health outcomes. Contemporary population-based data on use, risk factors and …

Integrative microbiomics in bronchiectasis exacerbations

M Mac Aogain, JK Narayana, PY Tiew, NABM Ali… - Nature medicine, 2021 - nature.com
Bronchiectasis, a progressive chronic airway disease, is characterized by microbial
colonization and infection. We present an approach to the multi-biome that integrates …

The global initiative for asthma (GINA): 25 years later

LP Boulet, HK Reddel, E Bateman… - European …, 2019 - publications.ersnet.org
The Global Initiative for Asthma (GINA) was launched in 1993 under the auspices of the
National Heart, Lung, and Blood Institute, National Institutes of Health, USA, and the World …

Understanding the immunology of asthma: Pathophysiology, biomarkers, and treatments for asthma endotypes

MD Gans, T Gavrilova - Paediatric respiratory reviews, 2020 - Elsevier
Asthma is a common disease in paediatrics and adults with a significant morbidity, mortality,
and financial burden worldwide. Asthma is now recognized as a heterogeneous disease …

Tractor uses local ancestry to enable the inclusion of admixed individuals in GWAS and to boost power

EG Atkinson, AX Maihofer, M Kanai, AR Martin… - Nature …, 2021 - nature.com
Admixed populations are routinely excluded from genomic studies due to concerns over
population structure. Here, we present a statistical framework and software package, Tractor …

Does monitoring goal progress promote goal attainment? A meta-analysis of the experimental evidence.

B Harkin, TL Webb, BPI Chang, A Prestwich… - Psychological …, 2016 - psycnet.apa.org
Control theory and other frameworks for understanding self-regulation suggest that
monitoring goal progress is a crucial process that intervenes between setting and attaining a …

The influence of dietary fatty acids on immune responses

U Radzikowska, AO Rinaldi, Z Çelebi Sözener… - Nutrients, 2019 - mdpi.com
Diet-derived fatty acids (FAs) are essential sources of energy and fundamental structural
components of cells. They also play important roles in the modulation of immune responses …

Role of viruses in asthma

T Jartti, K Bønnelykke, V Elenius… - Seminars in …, 2020 - Springer
Respiratory viral infections are the most important triggers of asthma exacerbations.
Rhinovirus (RV), the common cold virus, is clearly the most prevalent pathogen constantly …