The extracellular matrix (ECM) is one of the major components of tumors that plays multiple
crucial roles, including mechanical support, modulation of the microenvironment, and a …

Hyaluronan is an extracellular and cell-surface-associated polysaccharide that is
traditionally regarded as a biological'goo'that participates in lubricating joints or holding …

The cytoskeleton of animal cells is one of the most complicated and functionally versatile
structures, involved in processes such as endocytosis, cell division, intra-cellular transport …

Glioblastoma is both the most common and lethal primary malignant brain tumor. Extensive
multiplatform genomic characterization has provided a higher-resolution picture of the …

The invasion of neoplastic cells into healthy brain tissue is a pathologic hallmark of gliomas
and contributes to the failure of current therapeutic modalities (surgery, radiation and …

Gliomas are the most common primary brain tumors in adults. They arise in the glial tissue
and primarily occur in the brain. Low‐grade tumors of World Health Organization (WHO) …

Expression of receptor for hyaluronan-mediated motility (RHAMM), a breast cancer
susceptibility gene, is tightly controlled in normal tissues but elevated in many tumors …

Purpose The present review aims to emphasize that malignant gliomas are characterized by
the diffuse invasion of distant brain tissue by a myriad of single migrating cells that exhibit …

Glioblastoma (GBM) is the most common and lethal primary brain tumor. Over the past few
years tremendous genomic and proteomic characterization along with robust animal models …

It is well established that the large array of functions that a tumour cell has to fulfil to settle as
a metastasis in a distant organ requires cooperative activities between the tumour and the …