Corticotropin releasing factor (CRF) receptor signaling in the central nervous system: new molecular targets

RL Hauger, V Risbrough, O Brauns… - CNS & Neurological …, 2006 - ingentaconnect.com
Corticotropin-releasing factor (CRF) and the related urocortin peptides mediate behavioral,
cognitive, autonomic, neuroendocrine and immunologic responses to aversive stimuli by …

Nibbling at CRF receptor control of feeding and gastrocolonic motility

EP Zorrilla, Y Taché, GF Koob - Trends in pharmacological sciences, 2003 - cell.com
Inadequate pharmacological tools, until recently, hindered the understanding of the roles of
corticotropin-releasing factor (CRF) receptor subtypes in appetite regulation and …

Urocortin II: a member of the corticotropin-releasing factor (CRF) neuropeptide family that is selectively bound by type 2 CRF receptors

TM Reyes, K Lewis, MH Perrin, KS Kunitake… - Proceedings of the …, 2001 - pnas.org
Here we describe the cloning and initial characterization of a previously unidentified CRF-
related neuropeptide, urocortin II (Ucn II). Searches of the public human genome database …

Antimicrobial activity of a bovine hemoglobin fragment in the tick Boophilus microplus

AC Fogaça, PI da Silva, MTM Miranda… - Journal of Biological …, 1999 - jbc.org
Antifungal and antibacterial activities were detected in the hemolymph and gut contents of
the cattle tick, Boophilus microplus. A peptide with antibacterial activity from the tick gut …

Molecular recognition of corticotropin-releasing factor by its G-protein-coupled receptor CRFR1

AA Pioszak, NR Parker, K Suino-Powell… - Journal of Biological …, 2008 - jbc.org
The bimolecular interaction between corticotropin-releasing factor (CRF), a neuropeptide,
and its type 1 receptor (CRFR1), a class B G-protein-coupled receptor (GPCR), is crucial for …

Potent and long-acting corticotropin releasing factor (CRF) receptor 2 selective peptide competitive antagonists

J Rivier, J Gulyas, D Kirby, W Low… - Journal of medicinal …, 2002 - ACS Publications
We present evidence that members of the corticotropin releasing factor (CRF) family assume
distinct structures when interacting with the CRF1 and CRF2 receptors. Predictive methods …

Potent, structurally constrained agonists and competitive antagonists of corticotropin-releasing factor.

J Gulyas, C Rivier, M Perrin, SC Koerber… - Proceedings of the …, 1995 - pnas.org
Predictive methods, physicochemical measurements, and structure activity relationship
studies suggest that corticotropin-releasing factor (CRF; corticoliberin), its family members …

Structural requirements for peptidic antagonists of the corticotropin-releasing factor receptor (CRFR): development of CRFR2β-selective antisauvagine-30

A Rühmann, I Bonk, CR Lin, MG Rosenfeld… - Proceedings of the …, 1998 - pnas.org
Different truncated and conformationally constrained analogs of corticotropin-releasing
factor (CRF) were synthesized on the basis of the amino acid sequences of human/rat CRF …

Structure–activity relationship studies of gomesin: importance of the disulfide bridges for conformation, bioactivities, and serum stability

MA Fázio, VX Oliveira Jr, P Bulet… - Peptide Science …, 2006 - Wiley Online Library
Gomesin is an antimicrobial peptide isolated from hemocytes of the Brazilian spider
Acanthoscurria gomesiana that contains two disulfide bridges Cys2‐15/Cys6‐11 and …

Exon skip** in the gene encoding pituitary adenylate cyclase-activating polypeptide in salmon alters the expression of two hormones that stimulate growth hormone …

DB Parker, ME Power, P Swanson, J Rivier… - …, 1997 - academic.oup.com
In mammals, GRF and pituitary adenylate cyclase-activating polypeptide (PACAP) are
encoded in separate genes. We report here that in the salmon a 4.5-kilobase gene contains …