[HTML][HTML] Impact of gastrointestinal tract variability on oral drug absorption and pharmacokinetics: An UNGAP review
The absorption of oral drugs is frequently plagued by significant variability with potentially
serious therapeutic consequences. The source of variability can be traced back to …
serious therapeutic consequences. The source of variability can be traced back to …
[HTML][HTML] Re-thinking functional food development through a holistic approach
M Alongi, M Anese - Journal of functional foods, 2021 - Elsevier
Although the interest towards functional food has dramatically increased, several factors
jeopardize their effective development. A univocally recognized definition and a dedicated …
jeopardize their effective development. A univocally recognized definition and a dedicated …
[HTML][HTML] Artificial intelligence in drug discovery: what is realistic, what are illusions? Part 2: a discussion of chemical and biological data
Highlights•Drug discovery data and data from other sources are different in quantity and
characteristics.•This article underlines the difference of data from different domains.•In order …
characteristics.•This article underlines the difference of data from different domains.•In order …
Harnessing artificial intelligence for the next generation of 3D printed medicines
Artificial intelligence (AI) is redefining how we exist in the world. In almost every sector of
society, AI is performing tasks with super-human speed and intellect; from the prediction of …
society, AI is performing tasks with super-human speed and intellect; from the prediction of …
Let's talk about sex: Differences in drug therapy in males and females
Abstract Professor Henry Higgins in My Fair Lady said,'Why can'ta woman be more like a
man?'Perhaps unintended, such narration extends to the reality of current drug …
man?'Perhaps unintended, such narration extends to the reality of current drug …
ESPEN guideline on nutritional support for polymorbid medical inpatients
Background Disease-related malnutrition in polymorbid medical inpatients is a highly
prevalent syndrome associated with significantly increased morbidity, disability, short-and …
prevalent syndrome associated with significantly increased morbidity, disability, short-and …
[HTML][HTML] Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network
Although oral drug delivery is the preferred administration route and has been used for
centuries, modern drug discovery and development pipelines challenge conventional …
centuries, modern drug discovery and development pipelines challenge conventional …
Polysaccharide‐based porous biopolymers for enhanced bioaccessibility and bioavailability of bioactive food compounds: Challenges, advances, and opportunities
Bioactive food compounds, such as lycopene, curcumin, phytosterols, and resveratrol, have
received great attention due to their potential health benefits. However, these bioactive …
received great attention due to their potential health benefits. However, these bioactive …
Safety of probiotics: functional fruit beverages and nutraceuticals
Over the last decade, fruit juice consumption has increased. Their rise in popularity can be
attributed to the belief that they are a quick way to consuming a dietary portion of fruit …
attributed to the belief that they are a quick way to consuming a dietary portion of fruit …
Food effects on oral drug absorption: application of physiologically-based pharmacokinetic modeling as a predictive tool
The bioavailability of an orally administered small molecule is often dictated by drug-specific
physicochemical characteristics and is influenced by many biological processes. For …
physicochemical characteristics and is influenced by many biological processes. For …