[HTML][HTML] Impact of gastrointestinal tract variability on oral drug absorption and pharmacokinetics: An UNGAP review

Z Vinarov, M Abdallah, JAG Agundez… - European Journal of …, 2021 - Elsevier
The absorption of oral drugs is frequently plagued by significant variability with potentially
serious therapeutic consequences. The source of variability can be traced back to …

[HTML][HTML] Re-thinking functional food development through a holistic approach

M Alongi, M Anese - Journal of functional foods, 2021 - Elsevier
Although the interest towards functional food has dramatically increased, several factors
jeopardize their effective development. A univocally recognized definition and a dedicated …

[HTML][HTML] Artificial intelligence in drug discovery: what is realistic, what are illusions? Part 2: a discussion of chemical and biological data

A Bender, I Cortes-Ciriano - Drug Discovery Today, 2021 - Elsevier
Highlights•Drug discovery data and data from other sources are different in quantity and
characteristics.•This article underlines the difference of data from different domains.•In order …

Harnessing artificial intelligence for the next generation of 3D printed medicines

M Elbadawi, LE McCoubrey, FKH Gavins… - Advanced Drug Delivery …, 2021 - Elsevier
Artificial intelligence (AI) is redefining how we exist in the world. In almost every sector of
society, AI is performing tasks with super-human speed and intellect; from the prediction of …

Let's talk about sex: Differences in drug therapy in males and females

CM Madla, FKH Gavins, HA Merchant, M Orlu… - Advanced drug delivery …, 2021 - Elsevier
Abstract Professor Henry Higgins in My Fair Lady said,'Why can'ta woman be more like a
man?'Perhaps unintended, such narration extends to the reality of current drug …

ESPEN guideline on nutritional support for polymorbid medical inpatients

C Wunderle, F Gomes, P Schuetz, F Stumpf, P Austin… - Clinical nutrition, 2023 - Elsevier
Background Disease-related malnutrition in polymorbid medical inpatients is a highly
prevalent syndrome associated with significantly increased morbidity, disability, short-and …

[HTML][HTML] Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network

Z Vinarov, B Abrahamsson, P Artursson… - Advanced Drug Delivery …, 2021 - Elsevier
Although oral drug delivery is the preferred administration route and has been used for
centuries, modern drug discovery and development pipelines challenge conventional …

Polysaccharide‐based porous biopolymers for enhanced bioaccessibility and bioavailability of bioactive food compounds: Challenges, advances, and opportunities

A Ubeyitogullari, S Ahmadzadeh… - … Reviews in Food …, 2022 - Wiley Online Library
Bioactive food compounds, such as lycopene, curcumin, phytosterols, and resveratrol, have
received great attention due to their potential health benefits. However, these bioactive …

Safety of probiotics: functional fruit beverages and nutraceuticals

I Žuntar, Z Petric, D Bursać Kovačević, P Putnik - Foods, 2020 - mdpi.com
Over the last decade, fruit juice consumption has increased. Their rise in popularity can be
attributed to the belief that they are a quick way to consuming a dietary portion of fruit …

Food effects on oral drug absorption: application of physiologically-based pharmacokinetic modeling as a predictive tool

L Cheng, H Wong - Pharmaceutics, 2020 - mdpi.com
The bioavailability of an orally administered small molecule is often dictated by drug-specific
physicochemical characteristics and is influenced by many biological processes. For …