The prevalence of obesity continues to increase worldwide and represents one of the most
press-ing public health issues due to its associated morbidity, mortality, and health care …

Hypoxia is one of the most common and severe challenges to the maintenance of
homeostasis. Oxygen sensing is a property of all tissues, and the response to hypoxia is …

Essential Reproduction provides an accessible account of the fundamentals of reproduction
within the context of cutting-edge knowledge and examples of its application. The eighth …

Converging lines of evidence from epidemiological studies and animal models now indicate
that the origins of obesity and related metabolic disorders lie not only in the interaction …

In recent years, we've developed a much better grasp of the biological and other factors
associated with the development of obesity. Reflecting our evolving understanding of …

Leptin, the protein product of the obese (ob or Lep) gene, is a hormone synthesized by
adipocytes that signals available energy reserves to the brain, and thereby influences …

The prevalence of obesity and type 2 diabetes mellitus has increased rapidly over the past
few decades, and prevention efforts have not been successful. Fetal programming involves …

Reproductive function is dependent on energy resources. The role of weight, body
composition, fat distribution and the effect of diet have been largely investigated in …

As the prevalence of obesity has increased over the past few decades in the United States
among adults and pregnant women, so has the proportion of children who are obese. 1 …

Context: Increasing evidence suggests that adverse conditions during prenatal life are
associated with the development of chronic diseases in adult life. It is still unclear whether in …