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Pathogenesis of NEC: impact of an altered intestinal microbiome
Necrotizing enterocolitis (NEC), a disease most commonly seen in preterm infants, often
presents without warning and is associated with very high mortality and morbidity. Progress …
presents without warning and is associated with very high mortality and morbidity. Progress …
Pathogenesis of NEC: Role of the innate and adaptive immune response
Necrotizing enterocolitis (NEC) is a devastating disease in premature infants with high case
fatality and significant morbidity among survivors. Immaturity of intestinal host defenses …
fatality and significant morbidity among survivors. Immaturity of intestinal host defenses …
Temporal bacterial and metabolic development of the preterm gut reveals specific signatures in health and disease
Background The preterm microbiome is crucial to gut health and may contribute to
necrotising enterocolitis (NEC), which represents the most significant pathology affecting …
necrotising enterocolitis (NEC), which represents the most significant pathology affecting …
An exclusively human milk diet reduces necrotizing enterocolitis
K Herrmann, K Carroll - Breastfeeding Medicine, 2014 - liebertpub.com
Objective: This study tested the hypothesis that feeding an exclusively human milk (EHM)
diet to premature infants reduces the incidence of necrotizing enterocolitis (NEC) associated …
diet to premature infants reduces the incidence of necrotizing enterocolitis (NEC) associated …
[HTML][HTML] A novel role for necroptosis in the pathogenesis of necrotizing enterocolitis
Background & Aims Necrotizing enterocolitis (NEC) is a devastating disease of premature
infants characterized by Toll-like receptor 4 (TLR4)-dependent intestinal inflammation and …
infants characterized by Toll-like receptor 4 (TLR4)-dependent intestinal inflammation and …
Emerging biomarkers for prediction and early diagnosis of necrotizing enterocolitis in the era of metabolomics and proteomics
Necrotizing Enterocolitis (NEC) is a catastrophic disease affecting predominantly premature
infants and is characterized by high mortality and serious long-term consequences …
infants and is characterized by high mortality and serious long-term consequences …
Necrotizing enterocolitis and the preterm infant microbiome
JR Baranowski, EC Claud - … and Child Gastrointestinal Health: Advances in …, 2019 - Springer
Bacterial colonization patterns in preterm infants differ from those of their term counterparts
due to maternal microbial diversity, delivery mode, feeding methods, antibiotic use, and …
due to maternal microbial diversity, delivery mode, feeding methods, antibiotic use, and …
Neurodevelopmental outcome of infants who develop necrotizing enterocolitis: The gut-brain axis
Necrotizing enterocolitis (NEC) poses a significant risk for neurodevelopmental impairment
in extremely preterm infants. The gut microbiota shapes the development of the gut, immune …
in extremely preterm infants. The gut microbiota shapes the development of the gut, immune …
A critical question for NEC researchers: can we create a consensus definition of NEC that facilitates research progress?
PV Gordon, JR Swanson, BC MacQueen… - Seminars in …, 2017 - Elsevier
In the last decades the reported incidence of preterm necrotizing enterocolitis (NEC) has
been declining in large part due to implementing comprehensive NEC prevention initiatives …
been declining in large part due to implementing comprehensive NEC prevention initiatives …
Changing the paradigm of defining, detecting, and diagnosing NEC: Perspectives on Bell's stages and biomarkers for NEC
Better means to diagnose and define necrotizing enterocolitis are needed to guide clinical
practice and research. Adequacy of Bell's staging system for clinical practice and clarity of …
practice and research. Adequacy of Bell's staging system for clinical practice and clarity of …