Dengue virus: pathogenesis and potential for small molecule inhibitors
N Chauhan, KK Gaur, TR Asuru… - Bioscience reports, 2024 - portlandpress.com
Dengue, caused by dengue virus (DENV), is now endemic in nearly 100 countries and
infection incidence is reported in another 30 countries. Yearly an estimated 400 million …
infection incidence is reported in another 30 countries. Yearly an estimated 400 million …
Antimicrobial peptides for novel antiviral strategies in the current post‐COVID‐19 pandemic
The recent pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS‐
CoV‐2) has highlighted how urgent and necessary the discovery of new antiviral …
CoV‐2) has highlighted how urgent and necessary the discovery of new antiviral …
Back-pocket optimization of 2-aminopyrimidine-based macrocycles leads to potent EPHA2/GAK kinase inhibitors
Macrocyclization of acyclic compounds is a powerful strategy for improving inhibitor potency
and selectivity. Here we have optimized 2-aminopyrimidine-based macrocycles to use these …
and selectivity. Here we have optimized 2-aminopyrimidine-based macrocycles to use these …
Insight into Preventing Global Dengue Spread: Nanoengineered Niclosamide for Viral Infections
Millions of cases of dengue virus (DENV) infection yearly from Aedes mosquitoes stress the
need for effective antivirals. No current drug effectively combats dengue efficiently. Transient …
need for effective antivirals. No current drug effectively combats dengue efficiently. Transient …
Dengue virus infection and neurological manifestations: an update
Dengue virus is a flavivirus transmitted by the mosquitoes, Aedes aegypti and Aedes
albopictus. Dengue infection by all four serotypes (DEN 1 to 4) is endemic globally in …
albopictus. Dengue infection by all four serotypes (DEN 1 to 4) is endemic globally in …
Dengue virus pathogenesis and host molecular machineries
S Sinha, K Singh, YS Ravi Kumar, R Roy… - Journal of Biomedical …, 2024 - Springer
Dengue viruses (DENV) are positive-stranded RNA viruses belonging to the Flaviviridae
family. DENV is the causative agent of dengue, the most rapidly spreading viral disease …
family. DENV is the causative agent of dengue, the most rapidly spreading viral disease …
Dengue types 1 and 3 identified in travelers returning from Kathmandu, Nepal, during the October 2022 outbreak are related to strains recently identified in India
NS Zuckerman, E Schwartz, P Pandey, O Erster… - Viruses, 2023 - mdpi.com
Phylogenetic analysis of dengue serotypes 1 and 3, which were diagnosed in travelers and
Nepalese infected in Kathmandu during the October 2022 outbreak, revealed that both …
Nepalese infected in Kathmandu during the October 2022 outbreak, revealed that both …
[PDF][PDF] An In Silico Study: Phytochemical Compounds Screening of Garcinia atroviridis Griff. ex T. Anders as Anti-DENV.
Dengue virus (DENV) is still global problem and infecting millions of people a year. This
virus belongs to Flavivirus and consists of the structural and non-structural proteins including …
virus belongs to Flavivirus and consists of the structural and non-structural proteins including …
Natural Compounds and Their Analogs as Antivirals Against Dengue Virus: A Review
Dengue virus (DENV) continues to pose a significant global health challenge, causing
diseases such as dengue fever, dengue hemorrhagic fever, and dengue shock syndrome …
diseases such as dengue fever, dengue hemorrhagic fever, and dengue shock syndrome …
Targeting PI3Kγ Pathway for Treating Dengue virus Infection
FRS Santos, DF Valadão, JL Bambirra, TP Moreira… - Microbial …, 2024 - Elsevier
Dengue disease is a major problem worldwide, impacting millions of people annually with
no specific approved treatments. The pathogenesis of dengue is a complex interplay of viral …
no specific approved treatments. The pathogenesis of dengue is a complex interplay of viral …