Modular design in natural and biomimetic soft materials

AM Kushner, Z Guan - Angewandte Chemie International …, 2011‏ - Wiley Online Library
Under eons of evolutionary and environmental pressure, biological systems have developed
strong and lightweight peptide‐based polymeric materials by using the 20 naturally …

Structural disorder and protein elasticity

S Rauscher, R Pomès - Fuzziness: Structural disorder in protein …, 2012‏ - Springer
An emerging class of disordered proteins underlies the elasticity of many biological tissues.
Elastomeric proteins are essential to the function of biological machinery as diverse as the …

Proline and glycine control protein self-organization into elastomeric or amyloid fibrils

S Rauscher, S Baud, M Miao, FW Keeley, R Pomes - Structure, 2006‏ - cell.com
Elastin provides extensible tissues, including arteries and skin, with the propensity for elastic
recoil, whereas amyloid fibrils are associated with tissue-degenerative diseases, such as …

Secondary structure formation and LCST behavior of short elastin-like peptides

H Nuhn, HA Klok - Biomacromolecules, 2008‏ - ACS Publications
This contribution investigates the effects of chain length and chemical composition on the
secondary structure and LCST behavior of a library of short, elastin-like peptides based on …

How does solvation layer mobility affect protein structural dynamics?

JN Dahanayake, KR Mitchell-Koch - Frontiers in Molecular …, 2018‏ - frontiersin.org
Solvation is critical for protein structural dynamics. Spectroscopic studies have indicated
relationships between protein and solvent dynamics, and rates of gas binding to heme …

Temperature-responsive protein pores

Y Jung, H Bayley, L Movileanu - Journal of the American Chemical …, 2006‏ - ACS Publications
We describe temperature-responsive protein pores containing single elastin-like
polypeptide (ELP) loops. The ELP loops were placed within the cavity of the lumen of the α …

Computational smart polymer design based on elastin protein mutability

A Tarakanova, W Huang, AS Weiss, DL Kaplan… - Biomaterials, 2017‏ - Elsevier
Soluble elastin-like peptides (ELPs) can be engineered into a range of physical forms, from
hydrogels and scaffolds to fibers and artificial tissues, finding numerous applications in …

Structure–property relationships of elastin-like polypeptides: a review of experimental and computational studies

D López Barreiro, IJ Minten, JC Thies… - … Biomaterials Science & …, 2021‏ - ACS Publications
Elastin is a structural protein with outstanding mechanical properties (eg, elasticity and
resilience) and biologically relevant functions (eg, triggering responses like cell adhesion or …

[HTML][HTML] Self-assembly of short elastin-like amphiphilic peptides: Effects of temperature, molecular hydrophobicity and charge distribution

M Cao, Y Shen, Y Wang, X Wang, D Li - Molecules, 2019‏ - mdpi.com
A novel type of self-assembling peptides has been developed by introducing the basic
elastomeric β-turn units of elastin protein into the amphiphilic peptide molecules. The self …

Squeezing a single polypeptide through a nanopore

L Movileanu - Soft matter, 2008‏ - pubs.rsc.org
We have already seen a decade of single-molecule science involving protein nanopores,
and many lessons have been learned from the extensive studies in this exciting realm …