[HTML][HTML] The technology, opportunities and challenges of synthetic biological intelligence

BJ Kagan, C Gyngell, T Lysaght, VM Cole… - Biotechnology …, 2023 - Elsevier
Integrating neural cultures developed through synthetic biology methods with digital
computing has enabled the early development of Synthetic Biological Intelligence (SBI) …

First Organoid Intelligence (OI) workshop to form an OI community

IE Morales Pantoja, L Smirnova, AR Muotri… - Frontiers in Artificial …, 2023 - frontiersin.org
The brain is arguably the most powerful computation system known. It is extremely efficient
in processing large amounts of information and can discern signals from noise, adapt, and …

[HTML][HTML] Organoid intelligence (OI): the new frontier in biocomputing and intelligence-in-a-dish

L Smirnova, BS Caffo, DH Gracias, Q Huang… - Frontiers in …, 2023 - frontiersin.org
Biological computing (or biocomputing) offers potential advantages over silicon-based
computing in terms of faster decision-making, continuous learning during tasks, and greater …

Organoid intelligence (OI)–the ultimate functionality of a brain microphysiological system

L Smirnova, IEM Pantoja, T Hartung - ALTEX-Alternatives to animal …, 2023 - altex.org
Understanding brain function remains challenging as work with human and animal models
is complicated by compensatory mechanisms, while in vitro models have been too simple …

The promise and potential of brain organoids

L Smirnova, T Hartung - Advanced Healthcare Materials, 2024 - Wiley Online Library
Brain organoids are 3D in vitro culture systems derived from human pluripotent stem cells
that self‐organize to model features of the (develo**) human brain. This review examines …

Brain organoids and organoid intelligence from ethical, legal, and social points of view

T Hartung, IE Morales Pantoja… - Frontiers in Artificial …, 2024 - frontiersin.org
Human brain organoids, aka cerebral organoids or earlier “mini-brains”, are 3D cellular
models that recapitulate aspects of the develo** human brain. They show tremendous …

The implementation moonshot project for alternative chemical testing (IMPACT) toward a human exposome project

F Sillé, F Busquet, S Fitzpatrick, K Herrmann… - 2024 - kops.uni-konstanz.de
Zusammenfassung The Human Exposome Project aims to revolutionize our understanding
of how environmental exposures affect human health by systematically cataloging and …

Brain organoids: are they for real?

R Quirion - Frontiers in Science, 2023 - frontiersin.org
In 1965, Gordon E. Moore, the co-founder of Intel, observed that the number of transistors on
a single microchip doubles approximately every two years, while the cost of computers …

[HTML][HTML] Beyond consciousness: Ethical, legal, and social issues in human brain organoid research and application

M Kataoka, T Niikawa, N Nagaishi, TL Lee… - European Journal of …, 2024 - Elsevier
This study aims to provide a comprehensive review of the ethical, legal and social issues in
human brain organoid research, with a view to different types of research and applications …

Embodied Neural Systems Can Enable Iterative Investigations of Morally Relevant States

BJ Kagan, A Loeffler, JL Boyd… - Journal of …, 2024 - Soc Neuroscience
The development of new technologies is best accompanied by—ideally, preceded by—
serious ethical reflection. Difficulties in achieving this goal can arise because only after …