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[HTML][HTML] Metal oxide nanoparticles as biomedical materials
The development of new nanomaterials with high biomedical performance and low toxicity is
essential to obtain more efficient therapy and precise diagnostic tools and devices. Recently …
essential to obtain more efficient therapy and precise diagnostic tools and devices. Recently …
The landscape of nanoparticle-based siRNA delivery and therapeutic development
Five small interfering RNA (siRNA)-based therapeutics have been approved by the Food
and Drug Administration (FDA), namely patisiran, givosiran, lumasiran, inclisiran, and …
and Drug Administration (FDA), namely patisiran, givosiran, lumasiran, inclisiran, and …
Rekindling RNAi therapy: materials design requirements for in vivo siRNA delivery
With the recent FDA approval of the first siRNA‐derived therapeutic, RNA interference
(RNAi)‐mediated gene therapy is undergoing a transition from research to the clinical …
(RNAi)‐mediated gene therapy is undergoing a transition from research to the clinical …
Small interfering RNAs (siRNAs) in cancer therapy: a nano-based approach
G Mahmoodi Chalbatani, H Dana… - International journal …, 2019 - Taylor & Francis
Cancer is one of the most complex diseases that has resulted in multiple genetic disorders
and cellular abnormalities. Globally, cancer is the most common health concern disease that …
and cellular abnormalities. Globally, cancer is the most common health concern disease that …
Surface-engineered dendrimers in gene delivery
J Yang, Q Zhang, H Chang, Y Cheng - Chemical reviews, 2015 - ACS Publications
1. DENDRIMERS AND GENE DELIVERY Gene therapy represents a promising option for
the treatment of diseases such as inherited disorders, viral infections, and cancers. 1− 3 A …
the treatment of diseases such as inherited disorders, viral infections, and cancers. 1− 3 A …
Dendrimers as nanoscale vectors: Unlocking the bars of cancer therapy
Chemotherapy is the first choice in the treatment of cancer and is always preferred to other
approaches such as radiation and surgery, but it has never met the need of patients for a …
approaches such as radiation and surgery, but it has never met the need of patients for a …
Nanomedicine (s) under the microscope
Depending on the context, nanotechnologies developed as nanomedicines (nanosized
therapeutics and imaging agents) are presented as either a remarkable technological …
therapeutics and imaging agents) are presented as either a remarkable technological …
Nanomaterials: applications in cancer imaging and therapy
The application of nanomaterials (NMs) in biomedicine is increasing rapidly and offers
excellent prospects for the development of new non‐invasive strategies for the diagnosis …
excellent prospects for the development of new non‐invasive strategies for the diagnosis …
[HTML][HTML] PAMAM dendrimers as promising nanocarriers for RNAi therapeutics
Therapeutics based on RNA interference mechanisms are highly promising for the
management of several diseases including multi-drug resistant cancers. However, effective …
management of several diseases including multi-drug resistant cancers. However, effective …
Therapeutic siRNA: principles, challenges, and strategies
RNA interference (RNAi) is a remarkable endogenous regulatory pathway that can bring
about sequence-specific gene silencing. If harnessed effectively, RNAi could result in a …
about sequence-specific gene silencing. If harnessed effectively, RNAi could result in a …