The nucleosome remodelling and histone deacetylase (NuRD; also known as Mi-2) complex
regulates gene expression at the level of chromatin. The NuRD complex has been identified …

Transcription regulation through chromatin compaction and decompaction is regulated
through various chromatin-remodeling complexes such as nucleosome remodeling and …

MicroRNAs (miRNAs) are small, noncoding RNAs that can contribute to cancer development
and progression by acting as oncogenes or tumor suppressor genes. Recent studies have …

The ability of p53 to induce apoptosis plays an important role in tumor suppression. Here,
we describe a previously unknown posttranslational modification of the DNA-binding …

Polycomb genes encode critical regulators of both normal stem cells and cancer stem cells.
A gene signature that includes Polycomb genes and additional genes coregulated with …

Abstract The Nucleosome Remodeling and Deacetylase (NuRD) complex is one of the
major chromatin remodeling complexes found in cells. It plays an important role in regulating …

Chromatin remodelers are key players in the regulation of chromatin accessibility and
nucleosome positioning on the eukaryotic DNA, thereby essential for all DNA dependent …

MicroRNAs are important gene regulators that could play a profound role in tumorigenesis.
Our previous studies indicate that miR-145 is a tumor suppressor capable of inhibiting tumor …

Overexpression of MYC is a hallmark of many human cancers. The MYC oncogene has long
been thought to execute its neoplastic functions by acting as a classic transcription factor …

The family of myc proto‐oncogenes encodes transcription factors (c‐, N‐, and L‐Myc) that
regulate cell growth and proliferation and are involved in the etiology of diverse cancers …