Primary aldosteronism—a multidimensional syndrome
Primary aldosteronism is a common cause of hypertension and is a risk factor for
cardiovascular and renal morbidity and mortality, via mechanisms mediated by both …
cardiovascular and renal morbidity and mortality, via mechanisms mediated by both …
Primary aldosteronism: state-of-the-art review
We are witnessing a revolution in our understanding of primary aldosteronism (PA). In the
past 2 decades, we have learned that PA is a highly prevalent syndrome that is largely …
past 2 decades, we have learned that PA is a highly prevalent syndrome that is largely …
Proteomic and mechanistic analysis of spironolactone in patients at risk for HF
JP Ferreira, J Verdonschot, P Wang, A Pizard, T Collier… - Heart Failure, 2021 - jacc.org
Objectives This study sought to further understand the mechanisms underlying effect of
spironolactone and assessed its impact on multiple plasma protein biomarkers and their …
spironolactone and assessed its impact on multiple plasma protein biomarkers and their …
Engineered probiotics Clostridium butyricum‐pMTL007‐GLP‐1 improves blood pressure via producing GLP‐1 and modulating gut microbiota in spontaneous …
X Wang, W Chen, R **, X Xu, J Wei… - Microbial …, 2023 - Wiley Online Library
Hypertension is a significant risk factor of cardiovascular diseases (CVDs) with high
prevalence worldwide, the current treatment has multiple adverse effects and requires …
prevalence worldwide, the current treatment has multiple adverse effects and requires …
Subclinical primary aldosteronism and cardiovascular health: a population-based cohort study
BACKGROUND: Primary aldosteronism, characterized by overt renin-independent
aldosterone production, is a common but underrecognized form of hypertension and …
aldosterone production, is a common but underrecognized form of hypertension and …
Cardiac structure and function across the spectrum of aldosteronism: the atherosclerosis risk in communities study
JM Brown, MO Wijkman, BL Claggett, AM Shah… - …, 2022 - Am Heart Assoc
Background: Aldosterone production and mineralocorticoid receptor activation are
implicated in myocardial fibrosis and cardiovascular events. Methods: Cardiac structure and …
implicated in myocardial fibrosis and cardiovascular events. Methods: Cardiac structure and …
The impact of health care disparities on patients with heart failure
Heart failure (HF) remains a condition associated with high morbidity, mortality, and
associated costs. Although the number of medical and device-based therapies available to …
associated costs. Although the number of medical and device-based therapies available to …
Associating plasma aldosterone concentration with the prevalence of MAFLD in hypertensive patients: insights from a large-scale cross-sectional study
D Shen, X Cai, J Hu, S Song, Q Zhu, H Ma… - Frontiers in …, 2024 - frontiersin.org
Objective To explore the link between plasma aldosterone concentration (PAC) and the
prevalence of metabolic dysfunction-related fatty liver disease (MAFLD) in hypertensive …
prevalence of metabolic dysfunction-related fatty liver disease (MAFLD) in hypertensive …
Sex-Specific Associations of Aldosterone and Renin with Body Composition: A Population-Based Cohort Study
Context Renin–angiotensin–aldosterone system (RAAS) activation is closely linked to
obesity; however, the sex-specific associations between RAAS activity and body …
obesity; however, the sex-specific associations between RAAS activity and body …
Association of the trajectory of plasma aldosterone concentration with the risk of cardiovascular disease in patients with hypertension: a cohort study
X Cai, S Song, J Hu, Q Zhu, D Shen, W Yang, H Ma… - Scientific Reports, 2024 - nature.com
The purpose of this study was to determine the long-term pattern of plasma aldosterone
concentration (PAC) trajectories and to explore the relationship between PAC trajectory …
concentration (PAC) trajectories and to explore the relationship between PAC trajectory …