The relationship between pain and depression is thought to be bidirectional and the
underlying neurobiology 'shared'between the two conditions. However, these claims are …

Clinicians and scientists have begun to recognize that chronic pain and its treatment with
opioid analgesics may occasion hedonic dysregulation—a blunting of physiological and …

Abstract Recent innovations in Functional Magnetic Resonance Imaging (FMRI) have sped
data collection by enabling simultaneous scans of neural activity in multiple brain locations …

Brain corticostriatal circuits are important for understanding chronic pain and highly relevant
to motivation and cognitive processes. It has been demonstrated that in patients with chronic …

Pain is a multidimensional subjective experience with biological, psychological, and social
factors. Whereas acute pain can be a warning signal for the body to avoid excessive injury …

Understanding the mechanisms that underpin the transition from acute to chronic pain is
critical for the development of more effective and targeted treatments. There is growing …

Pain is the most distressing and disruptive feature of recurrent acute pancreatitis (RAP) and
chronic pancreatitis (CP) resulting in low quality of life (QOL) and disabilities. There is no …

Background Resting-state functional magnetic resonance imaging (Rs-fMRI) has confirmed
sensorimotor network (SMN) dysfunction in migraine without aura (MwoA). However, the …

Chronic pain and reward processing are understood to be reciprocally related to one
another. Previous studies of reward processing in chronic pain patients have reported …

Objective: The identification of a complementary test to confirm the diagnosis of FM. The
diagnosis of fibromyalgia (FM) is based on clinical features, but there is still no consensus …