Freezing of gait in Parkinson's disease: pathophysiology, risk factors and treatments

C Gao, J Liu, Y Tan, S Chen - Translational neurodegeneration, 2020 - Springer
Background Freezing of gait (FOG) is a common, disabling symptom of Parkinson's disease
(PD), but the mechanisms and treatments of FOG remain great challenges for clinicians and …

Freezing of gait: moving forward on a mysterious clinical phenomenon

JG Nutt, BR Bloem, N Giladi, M Hallett… - The Lancet …, 2011 - thelancet.com
Freezing of gait (FoG) is a unique and disabling clinical phenomenon characterised by brief
episodes of inability to step or by extremely short steps that typically occur on initiating gait …

Motor automaticity in Parkinson's disease

T Wu, M Hallett, P Chan - Neurobiology of disease, 2015 - Elsevier
Bradykinesia is the most important feature contributing to motor difficulties in Parkinson's
disease (PD). However, the pathophysiology underlying bradykinesia is not fully …

The therapeutic role of ketogenic diet in neurological disorders

D Pietrzak, K Kasperek, P Rękawek… - Nutrients, 2022 - mdpi.com
The ketogenic diet (KD) is a high-fat, low-carbohydrate and adequate-protein diet that has
gained popularity in recent years in the context of neurological diseases (NDs). The …

Mobility related physical and functional losses due to aging and disease-a motivation for lower limb exoskeletons

M Grimmer, R Riener, CJ Walsh, A Seyfarth - Journal of neuroengineering …, 2019 - Springer
Background Physical and functional losses due to aging and diseases decrease human
mobility, independence, and quality of life. This study is aimed at summarizing and …

[PDF][PDF] European physiotherapy guideline for Parkinson's disease

S Keus, M Munneke, M Graziano… - The Netherlands …, 2014 - parkinsonnet.nl
6 Guidelines((“guideline”[pt] OR “practice guideline”[pt] OR “health planning guidelines”[mh]
OR “consensus development conference”[pt] OR “consensus development conference …

Reliability of the new freezing of gait questionnaire: agreement between patients with Parkinson's disease and their carers

A Nieuwboer, L Rochester, T Herman… - Gait & posture, 2009 - Elsevier
Freezing of gait (FOG) is difficult to measure due to its unpredictable occurrence. This study
investigated:(1) whether the new freezing of gait questionnaire (NFOG-Q) is a reliable …

Measuring freezing of gait during daily-life: an open-source, wearable sensors approach

M Mancini, VV Shah, S Stuart, C Curtze… - … of neuroengineering and …, 2021 - Springer
Background Although a growing number of studies focus on the measurement and detection
of freezing of gait (FoG) in laboratory settings, only a few studies have attempted to measure …

Freezing of gait and fall detection in Parkinson's disease using wearable sensors: a systematic review

AL Silva de Lima, LJW Evers, T Hahn, L Bataille… - Journal of …, 2017 - Springer
Despite the large number of studies that have investigated the use of wearable sensors to
detect gait disturbances such as Freezing of gait (FOG) and falls, there is little consensus …

Targeted activation of midbrain neurons restores locomotor function in mouse models of parkinsonism

D Masini, O Kiehn - Nature communications, 2022 - nature.com
The pedunculopontine nucleus (PPN) is a locomotor command area containing
glutamatergic neurons that control locomotor initiation and maintenance. These motor …