A century of dissolution research: from Noyes and Whitney to the biopharmaceutics classification system
A Dokoumetzidis, P Macheras - International journal of pharmaceutics, 2006 - Elsevier
Dissolution research started to develop about 100 years ago as a field of physical chemistry
and since then important progress has been made. However, explicit interest in drug related …
and since then important progress has been made. However, explicit interest in drug related …
Amorphous drug delivery systems: molecular aspects, design, and performance
The biopharmaceutical properties—especially the solubility and permeability—of a molecule
contribute to its overall therapeutic efficacy. The newer tools of drug discovery have caused …
contribute to its overall therapeutic efficacy. The newer tools of drug discovery have caused …
[PDF][PDF] Review on solubility enhancement techniques for hydrophobic drugs
A Kumar, SK Sahoo, K Padhee, PS Kochar… - Pharmacie …, 2011 - researchgate.net
Among all newly discovered chemical entities about 40% drugs are lipophillic and fail to
reach market due to their poor aqueous solubility. For orally administered drugs solubility is …
reach market due to their poor aqueous solubility. For orally administered drugs solubility is …
Biopharmaceutics classification and intestinal absorption study of apigenin
J Zhang, D Liu, Y Huang, Y Gao, S Qian - International journal of …, 2012 - Elsevier
The aim of the study was to characterize the biopharmaceutics classification system (BCS)
category of apigenin (AP) using intrinsic dissolution rate (IDR) and rat intestinal permeability …
category of apigenin (AP) using intrinsic dissolution rate (IDR) and rat intestinal permeability …
[BOG][B] Pharmaceutical dosage forms-tablets
LL Augsburger, SW Hoag - 2016 - books.google.com
The ultimate goal of drug product development is to design a system that maximizes the
therapeutic potential of the drug substance and facilitates its access to patients …
therapeutic potential of the drug substance and facilitates its access to patients …