Rescuing the last-line polymyxins: achievements and challenges

SC Nang, MAK Azad, T Velkov, QT Zhou, J Li - Pharmacological reviews, 2021 - Elsevier
Antibiotic resistance is a major global health challenge and, worryingly, several key Gram
negative pathogens can become resistant to most currently available antibiotics. Polymyxins …

Antimicrobial resistance and virulence: a successful or deleterious association in the bacterial world?

A Beceiro, M Tomás, G Bou - Clinical microbiology reviews, 2013 - journals.asm.org
Hosts and bacteria have coevolved over millions of years, during which pathogenic bacteria
have modified their virulence mechanisms to adapt to host defense systems. Although the …

Mechanisms of polymyxin resistance

JH Moffatt, M Harper, JD Boyce - Polymyxin antibiotics: From laboratory …, 2019 - Springer
Polymyxin antibiotics are increasingly being used as last-line therapeutic options against a
number of multidrug resistant bacteria. These antibiotics show strong bactericidal activity …

Vibrio–bivalve interactions in health and disease

D Destoumieux‐Garzón, L Canesi… - Environmental …, 2020 - Wiley Online Library
In the marine environment, bivalve mollusks constitute habitats for bacteria of the
Vibrionaceae family. Vibrios belong to the microbiota of healthy oysters and mussels, which …

The importance of microbes in animal development: lessons from the squid-vibrio symbiosis

MJ McFall-Ngai - Annual review of microbiology, 2014 - annualreviews.org
Developmental biology is among the many subdisciplines of the life sciences being
transformed by our increasing awareness of the role of coevolved microbial symbionts in …

The emergence of Vibrio pathogens in Europe: ecology, evolution, and pathogenesis (Paris, 11–12th March 2015)

FL Roux, KM Wegner, C Baker-Austin… - Frontiers in …, 2015 - frontiersin.org
Global change has caused a worldwide increase in reports of Vibrio-associated diseases
with ecosystem-wide impacts on humans and marine animals. In Europe, higher prevalence …

Bacterial diseases in marine bivalves

MA Travers, KB Miller, A Roque… - Journal of invertebrate …, 2015 - Elsevier
Bivalve aquaculture is seriously affected by many bacterial pathogens that cause high
losses in hatcheries as well as in natural beds. A number of Vibrio species, but also …

New insights into pathogenic Vibrios affecting bivalves in hatcheries: present and future prospects

J Dubert, JL Barja, JL Romalde - Frontiers in microbiology, 2017 - frontiersin.org
Hatcheries constitute nowadays the only viable solution to support the husbandry of bivalve
molluscs due to the depletion and/or overexploitation of their natural beds. Hatchery …

Oysters and vibrios as a model for disease dynamics in wild animals

F Le Roux, KM Wegner, MF Polz - Trends in microbiology, 2016 - cell.com
Disease dynamics in the wild are influenced by a number of ecological and evolutionary
factors not addressed by traditional laboratory-based characterization of pathogens. Here …

High temperature aggravates mortalities of the Pacific oyster (Crassostrea gigas) infected with Vibrio: A perspective from homeostasis of digestive microbiota and …

X Li, C Shi, B Yang, Q Li, S Liu - Aquaculture, 2023 - Elsevier
Long-lasting high temperature and bacterial exposure are two critical environmental factors
contributing to the mass mortality of oysters in summer. In this study, we investigated the …