The revised Trypanosoma cruzi subspecific nomenclature: rationale, epidemiological relevance and research applications

B Zingales, MA Miles, DA Campbell… - Infection, genetics and …, 2012 - Elsevier
The protozoan Trypanosoma cruzi, its mammalian reservoirs, and vectors have existed in
nature for millions of years. The human infection, named Chagas disease, is a major public …

Trypanosoma cruzi genetic diversity: Something new for something known about Chagas disease manifestations, serodiagnosis and drug sensitivity

B Zingales - Acta tropica, 2018 - Elsevier
The genetic diversity of Trypanosoma cruzi, the protozoan agent of Chagas disease, is
widely recognized. At present, T. cruzi is partitioned into seven discrete ty** units (DTUs) …

Chagas disease in the United States: a public health approach

C Bern, LA Messenger, JD Whitman… - Clinical microbiology …, 2019 - Am Soc Microbiol
Trypanosoma cruzi is the etiological agent of Chagas disease, usually transmitted by
triatomine vectors. An estimated 20 to 30% of infected individuals develop potentially lethal …

Trypanosoma cruzi genetic diversity: impact on transmission cycles and Chagas disease

B Zingales, DC Bartholomeu - Memórias do instituto oswaldo cruz, 2022 - SciELO Brasil
Trypanosoma cruzi, the agent of Chagas disease (ChD), exhibits remarkable biological and
genetic diversity, along with eco-epidemiological complexity. In order to facilitate …

Between a bug and a hard place: Trypanosoma cruzi genetic diversity and the clinical outcomes of Chagas disease

LA Messenger, MA Miles, C Bern - Expert review of anti-infective …, 2015 - Taylor & Francis
Over the last 30 years, concomitant with successful transnational disease control programs
across Latin America, Chagas disease has expanded from a neglected, endemic parasitic …

Genetic diversity of Trypanosoma cruzi in bats, and multilocus phylogenetic and phylogeographical analyses supporting Tcbat as an independent DTU (discrete …

L Lima, O Espinosa-Álvarez, PA Ortiz, JA Trejo-Varón… - Acta tropica, 2015 - Elsevier
Trypanosoma cruzi is a complex of phenotypically and genetically diverse isolates
distributed in six discrete ty** units (DTUs) designated as TcI–TcVI. Five years ago, T …

A new genotype of Trypanosoma cruzi associated with bats evidenced by phylogenetic analyses using SSU rDNA, cytochrome b and Histone H2B genes and …

A Marcili, L Lima, M Cavazzana, ACV Junqueira… - Parasitology, 2009 - cambridge.org
We characterized 15 Trypanosoma cruzi isolates from bats captured in the Amazon, Central
and Southeast Brazilian regions. Phylogenetic relationships among T. cruzi lineages using …

Mechanisms of cellular invasion by intracellular parasites

DM Walker, S Oghumu, G Gupta, BS McGwire… - Cellular and molecular …, 2014 - Springer
Numerous disease-causing parasites must invade host cells in order to prosper.
Collectively, such pathogens are responsible for a staggering amount of human sickness …

The molecular epidemiology and phylogeography of Trypanosoma cruzi and parallel research on Leishmania: looking back and to the future

MA Miles, MS Llewellyn, MD Lewis, M Yeo, R Baleela… - Parasitology, 2009 - cambridge.org
Trypanosoma cruzi is the protozoan agent of Chagas disease, and the most important
parasitic disease in Latin America. Protozoa of the genus Leishmania are global agents of …

Chagas Cardiomyopathy Manifestations and Trypanosoma cruzi Genotypes Circulating in Chronic Chagasic Patients

JD Ramírez, F Guhl, LM Rendón, F Rosas… - PLoS Neglected …, 2010 - journals.plos.org
Chagas disease caused by Trypanosoma cruzi is a complex disease that is endemic and an
important problem in public health in Latin America. The T. cruzi parasite is classified into six …