Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …

The mechanical properties of soft tissues play a key role in studying human injuries and their
mitigation strategies. While such properties are indispensable for computational modelling …

Abstract The three-dimensional (3D) multicellular tumor spheroids (MCTs) model is
becoming an essential tool in cancer research as it expresses an intermediate complexity …

One of the most promising fields for shape‐memory polymers is the biomedical field. Shape‐
memory polymers that can be triggered by various (physiological) conditions such as …

The concept that progression of cancer is regulated by interactions of cancer cells with their
microenvironment was postulated by Stephen Paget over a century ago. Contemporary …

Physical forces have a crucial role in tumor progression and cancer treatment. The
application of principles of engineering and physical sciences to oncology has provided …

Only a fraction of cancer patients benefits from immune checkpoint inhibitors. This may be
partly due to the dense extracellular matrix (ECM) that forms a barrier for T cells. Comparing …

Biomedical electronic devices are interfaced with the human body to extract precise medical
data and to interfere with tissue function by providing electrical stimuli. In this Review, we …

Tumors are stiff and data suggest that the extracellular matrix stiffening that correlates with
experimental mammary malignancy drives tumor invasion and metastasis. Nevertheless, the …

Immunotherapy based on immune checkpoint inhibitors has evolved into a new pillar of
cancer treatment in clinics, but dealing with treatment resistance (either primary or acquired) …