The roles of the gut microbiota and chronic low-grade inflammation in older adults with frailty

YS Xu, XJ Liu, XX Liu, D Chen, MM Wang… - Frontiers in Cellular …, 2021 - frontiersin.org
Frailty is a major public issue that affects the physical health and quality of life of older
adults, especially as the population ages. Chronic low-grade inflammation has been …

HIV, opioid use, and alterations to the gut microbiome: elucidating independent and synergistic effects

S Satish, Y Abu, D Gomez, R Kumar Dutta… - Frontiers in …, 2023 - frontiersin.org
Background The microbiome is essential to immune development, defense against
pathogens, and modulation of inflammation. Microbial dysbiosis has been reported in …

[HTML][HTML] Impaired gut microbiota-mediated short-chain fatty acid production precedes morbidity and mortality in people with HIV

I Sereti, ML Verburgh, J Gifford, A Lo, A Boyd, E Verheij… - Cell reports, 2023 - cell.com
Antiretroviral therapy (ART) has dramatically lengthened lifespan among people with HIV
(PWH), but this population experiences heightened rates of inflammation-related …

Gut microbiota, circulating inflammatory markers and metabolites, and carotid artery atherosclerosis in HIV infection

Z Wang, BA Peters, MK Bryant, DB Hanna, T Schwartz… - Microbiome, 2023 - Springer
Background Alterations in gut microbiota have been implicated in HIV infection and
cardiovascular disease. However, how gut microbial alterations relate to host inflammation …

Gut microbiota, plasma metabolomic profiles, and carotid artery atherosclerosis in HIV infection

Z Wang, BA Peters, M Usyk, J **ng… - … , and vascular biology, 2022 - ahajournals.org
Background: Alterations in gut microbiota and blood metabolomic profiles have been
implicated in HIV infection and cardiovascular disease. However, it remains unclear whether …

Exploring the interplay between antiretroviral therapy and the gut-oral microbiome axis in people living with HIV

A Narayanan, O Kieri, J Vesterbacka, L Manoharan… - Scientific Reports, 2024 - nature.com
The gut and oral microbiome is altered in people living with HIV (PLWH). While antiretroviral
treatment (ART) is pivotal in restoring immune function in PLWH, several studies have …

The altered metabolites contributed by dysbiosis of gut microbiota are associated with microbial translocation and immune activation during HIV infection

Y Zhang, Z **e, J Zhou, Y Li, C Ning, Q Su… - Frontiers in …, 2023 - frontiersin.org
Background The immune activation caused by microbial translocation has been considered
to be a major driver of HIV infection progression. The dysbiosis of gut microbiota has been …

Evolution of the gut microbiome in HIV-exposed uninfected and unexposed infants during the first year of life

CL Jackson, DN Frank, CE Robertson, D Ir… - Mbio, 2022 - journals.asm.org
ABSTRACT HIV-exposed uninfected infants (HEU) have abnormal immunologic functions
and increased infectious morbidity in the first 6 months of life, which gradually decreases …

Distinct Gut Microbiota Signatures Associated With Progression of Atherosclerosis in People Living With Human Immunodeficiency Virus

M Masiá, JA García, J García-Abellán… - The Journal of …, 2024 - academic.oup.com
Background The relationship of microbiota composition dynamics and the progression of
subclinical atherosclerosis in people with human immunodeficiency virus (PWH) remains …

Gut microbiota and cognitive function among women living with HIV

S Hua, BA Peters, S Lee, K Fitzgerald… - Journal of …, 2023 - journals.sagepub.com
Background: Altered gut microbiota has been associated with cognitive dysfunction and
Alzheimer's disease, but little is known among people living with HIV. Objective: To examine …