A time to fast

A Di Francesco, C Di Germanio, M Bernier, R De Cabo - Science, 2018 - science.org
Nutrient composition and caloric intake have traditionally been used to devise optimized
diets for various phases of life. Adjustment of meal size and frequency have emerged as …

Time-restricted eating: benefits, mechanisms, and challenges in translation

P Regmi, LK Heilbronn - Iscience, 2020 - cell.com
Eating out of phase with daily circadian rhythms induces metabolic desynchrony in
peripheral metabolic organs and may increase chronic disease risk. Time-restricted eating …

Randomized controlled trial for time-restricted eating in healthy volunteers without obesity

Z **e, Y Sun, Y Ye, D Hu, H Zhang, Z He… - Nature …, 2022 - nature.com
Time-restricted feeding (TRF) improves metabolic health. Both early TRF (eTRF, food intake
restricted to the early part of the day) and mid-day TRF (mTRF, food intake restricted to the …

[HTML][HTML] Early time-restricted feeding improves 24-hour glucose levels and affects markers of the circadian clock, aging, and autophagy in humans

H Jamshed, RA Beyl, DL Della Manna, ES Yang… - Nutrients, 2019 - mdpi.com
Time-restricted feeding (TRF) is a form of intermittent fasting that involves having a longer
daily fasting period. Preliminary studies report that TRF improves cardiometabolic health in …

[HTML][HTML] Early time-restricted feeding improves insulin sensitivity, blood pressure, and oxidative stress even without weight loss in men with prediabetes

EF Sutton, R Beyl, KS Early, WT Cefalu, E Ravussin… - Cell metabolism, 2018 - cell.com
Intermittent fasting (IF) improves cardiometabolic health; however, it is unknown whether
these effects are due solely to weight loss. We conducted the first supervised controlled …

Effects of time-restricted feeding (16/8) combined with a low-sugar diet on the management of non-alcoholic fatty liver disease: a randomized controlled trial

H Kord-Varkaneh, A Salehi-Sahlabadi, GM Tinsley… - Nutrition, 2023 - Elsevier
Objectives Emerging studies have employed time-restricted feeding (TRF) and a low-sugar
diet alone in the management of non-alcoholic fatty liver disease (NAFLD), but their …

Nuclear receptor subfamily 1 group D member 1 regulates circadian activity of NLRP3 inflammasome to reduce the severity of fulminant hepatitis in mice

B Pourcet, M Zecchin, L Ferri, J Beauchamp, S Sitaula… - Gastroenterology, 2018 - Elsevier
Background & Aims The innate immune system responds not only to bacterial signals, but
also to non-infectious danger-associated molecular patterns that activate the NLRP3 …

Timed high‐fat diet resets circadian metabolism and prevents obesity

H Sherman, Y Genzer, R Cohen, N Chapnik… - The FASEB …, 2012 - Wiley Online Library
Disruption of circadian rhythms leads to obesity and metabolic disorders. Timed restricted
feeding (RF) provides a time cue and resets the circadian clock, leading to better health. In …

Time-restricted feeding and risk of metabolic disease: a review of human and animal studies

J Rothschild, KK Hoddy, P Jambazian… - Nutrition …, 2014 - academic.oup.com
Abstract Time-restricted feeding (TRF), a key component of intermittent fasting regimens, has
gained considerable attention in recent years. TRF allows ad libitum energy intake within …

Complex physiology and clinical implications of time-restricted eating

MC Petersen, MR Gallop, SF Ramos… - Physiological …, 2022 - journals.physiology.org
Time-restricted eating (TRE) is a dietary intervention that limits food consumption to a
specific time window each day. The effect of TRE on body weight and physiological …