[HTML][HTML] Sex and gender differences in developmental programming of metabolism

L Dearden, SG Bouret, SE Ozanne - Molecular metabolism, 2018 - Elsevier
Background The early life environment experienced by an individual in utero and during the
neonatal period is a major factor in sha** later life disease risk-including susceptibility to …

[HTML][HTML] Epigenetics in adipose tissue, obesity, weight loss, and diabetes

JA Martínez, FI Milagro, KJ Claycombe… - Advances in nutrition, 2014 - Elsevier
Given the role that diet and other environmental factors play in the development of obesity
and type 2 diabetes, the implication of different epigenetic processes is being investigated …

The impact of metabolism on DNA methylation

CL Ulrey, L Liu, LG Andrews… - Human molecular …, 2005 - academic.oup.com
Methylation of genomic cytosines is one of the best characterized epigenetic mechanisms,
and investigation of its relationship with other biochemical pathways represents a critical …

[HTML][HTML] Retinol, retinoic acid, and retinol-binding protein 4 are differentially associated with cardiovascular disease, type 2 diabetes, and obesity: an overview of …

T Olsen, R Blomhoff - Advances in Nutrition, 2020 - Elsevier
Vitamin A is a fat-soluble essential nutrient obtained from plant-and animal-based sources
that has roles in growth, vision, and metabolism. Vitamin A circulates mainly as retinol bound …

[HTML][HTML] Homocysteine imbalance: a pathological metabolic marker

KL Schalinske, AL Smazal - Advances in nutrition, 2012 - Elsevier
Perturbations in methyl group metabolism and homocysteine balance have emerged over
the past few decades as having defining roles in a number of pathological conditions …

Betaine homocysteine S-methyltransferase: just a regulator of homocysteine metabolism?

MA Pajares, D Pérez-Sala - Cellular and Molecular Life Sciences CMLS, 2006 - Springer
Betaine homocysteine methyltransferase (BHMT), a Zn 2+-dependent
thiolmethyltransferase, contributes to the regulation of homocysteine levels, increases in …

Streptozotocin-induced diabetes in the rat is associated with enhanced tissue hydrogen sulfide biosynthesis

M Yusuf, BTK Huat, A Hsu, M Whiteman… - Biochemical and …, 2005 - Elsevier
This investigation is aimed to determine whether the biosynthesis of H2S, an endogenous
vasodilator gas, is altered in the streptozotocin-diabetic rat. Plasma H2S concentration as …

[HTML][HTML] Regulation of homocysteine metabolism and methylation in human and mouse tissues

NC Chen, F Yang, LM Capecci, Z Gu… - The FASEB …, 2010 - ncbi.nlm.nih.gov
Hyperhomocysteinemia is an independent risk factor for cardiovascular disease.
Homocysteine (Hcy) metabolism involves multiple enzymes; however, tissue Hcy …

Homocysteine metabolism and its relation to health and disease

KT Williams, KL Schalinske - Biofactors, 2010 - Wiley Online Library
Homocysteine is a metabolic intermediate in methyl group metabolism that is dependent on
a number of nutritional B‐vitamin cofactors. An emerging aspect of homocysteine …

S-adenosylmethionine and its products

MA Grillo, S Colombatto - Amino acids, 2008 - Springer
S-adenosylmethionine is involved in many processes, mainly methylation, polyamine
synthesis and radical-based catalysis. It is synthesised through the catalysis of differently …