Thyroid hormones and cardiovascular disease

A Jabbar, A **itore, SHS Pearce, A Zaman… - Nature Reviews …, 2017 - nature.com
Myocardial and vascular endothelial tissues have receptors for thyroid hormones and are
sensitive to changes in the concentrations of circulating thyroid hormones. The importance …

The role of thyroglobulin in thyroid hormonogenesis

CE Citterio, HM Targovnik, P Arvan - Nature Reviews Endocrinology, 2019 - nature.com
In humans, the thyroid hormones T3 and T4 are synthesized in the thyroid gland in a
process that crucially involves the iodoglycoprotein thyroglobulin. The overall structure of …

2016 American Thyroid Association guidelines for diagnosis and management of hyperthyroidism and other causes of thyrotoxicosis

DS Ross, HB Burch, DS Cooper, MC Greenlee… - Thyroid, 2016 - liebertpub.com
Background: Thyrotoxicosis has multiple etiologies, manifestations, and potential therapies.
Appropriate treatment requires an accurate diagnosis and is influenced by coexisting …

Hyperthyroidism and other causes of thyrotoxicosis: management guidelines of the American Thyroid Association and American Association of Clinical …

… Thyroid Association and American Association of … - Thyroid, 2011 - liebertpub.com
Background: Thyrotoxicosis has multiple etiologies, manifestations, and potential therapies.
Appropriate treatment requires an accurate diagnosis and is influenced by coexisting …

The 2015 European Thyroid Association guidelines on diagnosis and treatment of endogenous subclinical hyperthyroidism

B Biondi, L Bartalena, DS Cooper… - European thyroid …, 2015 - etj.bioscientifica.com
Endogenous subclinical hyperthyroidism (SHyper) is caused by Graves' disease,
autonomously functioning thyroid nodules and multinodular goitre. Its diagnosis is based on …

Thyroid and cardiovascular disease: research agenda for enhancing knowledge, prevention, and treatment

AR Cappola, AS Desai, M Medici, LS Cooper, D Egan… - Circulation, 2019 - ahajournals.org
Thyroid hormones have long been known to have a range of effects on the cardiovascular
system. However, significant knowledge gaps exist concerning the precise molecular and …

The clinical significance of subclinical thyroid dysfunction

B Biondi, DS Cooper - Endocrine reviews, 2008 - academic.oup.com
Subclinical thyroid disease (SCTD) is defined as serum free T4 and free T3 levels within
their respective reference ranges in the presence of abnormal serum TSH levels. SCTD is …

Subclinical thyroid disease

DS Cooper, B Biondi - The Lancet, 2012 - thelancet.com
Subclinical thyroid diseases—subclinical hyperthyroidism and subclinical hypothyroidism—
are common clinical entities that encompass mild degrees of thyroid dysfunction. The clinical …

Thyroid hormone action in the heart

GJ Kahaly, WH Dillmann - Endocrine reviews, 2005 - academic.oup.com
The heart is a major target organ for thyroid hormone action, and marked changes occur in
cardiac function in patients with hypo-or hyperthyroidism. T3-induced changes in cardiac …

The spectrum of thyroid disease and risk of new onset atrial fibrillation: a large population cohort study

C Selmer, JB Olesen, ML Hansen, J Lindhardsen… - Bmj, 2012 - bmj.com
Objectives To examine the risk of atrial fibrillation in relation to the whole spectrum of thyroid
function in a large cohort of patients. Design Population based cohort study of general …