Important flavonoids and their role as a therapeutic agent
Flavonoids are phytochemical compounds present in many plants, fruits, vegetables, and
leaves, with potential applications in medicinal chemistry. Flavonoids possess a number of …
leaves, with potential applications in medicinal chemistry. Flavonoids possess a number of …
Molecular mechanisms of neurodegeneration in Alzheimer's disease
L Crews, E Masliah - Human molecular genetics, 2010 - academic.oup.com
Alzheimer's disease (AD) is characterized by cognitive impairment, progressive
neurodegeneration and formation of amyloid-β (Aβ)-containing plaques and neurofibrillary …
neurodegeneration and formation of amyloid-β (Aβ)-containing plaques and neurofibrillary …
Neurodegenerative disease and adult neurogenesis
The generation and cell death of newly generated cells have critical roles in brain
development and maintenance in the embryonic and adult brain. Alterations in these …
development and maintenance in the embryonic and adult brain. Alterations in these …
Resveratrol: a focus on several neurodegenerative diseases
E Tellone, A Galtieri, A Russo… - … medicine and cellular …, 2015 - Wiley Online Library
Molecules of the plant world are proving their effectiveness in countering, slowing down, and
regressing many diseases. The resveratrol for its intrinsic properties related to its stilbene …
regressing many diseases. The resveratrol for its intrinsic properties related to its stilbene …
Early-life stress lastingly alters the neuroinflammatory response to amyloid pathology in an Alzheimer's disease mouse model
L Hoeijmakers, SR Ruigrok, A Amelianchik… - Brain, behavior, and …, 2017 - Elsevier
Exposure to stress during the sensitive period of early-life increases the risk to develop
cognitive impairments and psychopathology later in life. In addition, early-life stress (ES) …
cognitive impairments and psychopathology later in life. In addition, early-life stress (ES) …
The Toxicity of Amyloid β Oligomers
In this review, we elucidate the mechanisms of A β oligomer toxicity which may contribute to
Alzheimer's disease (AD). In particular, we discuss on the interaction of A β oligomers with …
Alzheimer's disease (AD). In particular, we discuss on the interaction of A β oligomers with …
B-vitamin deprivation induces hyperhomocysteinemia and brain S-adenosylhomocysteine, depletes brain S-adenosylmethionine, and enhances PS1 and BACE …
A Fuso, V Nicolia, RA Cavallaro, L Ricceri… - Molecular and cellular …, 2008 - Elsevier
Etiological and molecular studies on the sporadic form of Alzheimer's disease have yet to
determine the underlying mechanisms of neurodegeneration. Hyperhomocysteinemia is …
determine the underlying mechanisms of neurodegeneration. Hyperhomocysteinemia is …
Increased accumulation of intraneuronal amyloid β in HIV-infected patients
CL Achim, A Adame, W Dumaop, IP Everall… - Journal of Neuroimmune …, 2009 - Springer
In recent years, human immunodeficiency virus (HIV)-infected patients under highly active
anti-retroviral therapy (HAART) regimens have shown a markedly improved general clinical …
anti-retroviral therapy (HAART) regimens have shown a markedly improved general clinical …
Resveratrol and neurodegenerative diseases: activation of SIRT1 as the potential pathway towards neuroprotection
M Pallàs, G Casadesús, MA Smith… - Current …, 2009 - ingentaconnect.com
One of the current problems in medicine research is the development of safe drugs for the
treatment of neurological disorders. Furthermore, there is a close relationship between the …
treatment of neurological disorders. Furthermore, there is a close relationship between the …
Protective effects of flavonoids against Alzheimer's disease-related neural dysfunctions
M Bakhtiari, Y Panahi, J Ameli, B Darvishi - Biomedicine & …, 2017 - Elsevier
Senile ages of human life is mostly associated with developmental of several neurological
complicated conditions including decreased cognition and reasoning, increased memory …
complicated conditions including decreased cognition and reasoning, increased memory …