Microsporidiosis in humans

B Han, G Pan, LM Weiss - Clinical Microbiology Reviews, 2021 - journals.asm.org
Microsporidia are obligate intracellular pathogens identified∼ 150 years ago as the cause
of pébrine, an economically important infection in silkworms. There are about 220 genera …

Microsporidia: obligate intracellular pathogens within the fungal kingdom

B Han, LM Weiss - Microbiology spectrum, 2017 - journals.asm.org
Microsporidia are obligate intracellular pathogens related to Fungi. These organisms have a
unique invasion organelle, the polar tube, which upon appropriate environmental …

Phylogenomics supports microsporidia as the earliest diverging clade of sequenced fungi

S Capella-Gutiérrez, M Marcet-Houben, T Gabaldón - BMC biology, 2012 - Springer
Background Microsporidia is one of the taxa that have experienced the most dramatic
taxonomic reclassifications. Once thought to be among the earliest diverging eukaryotes, the …

Tissue destruction and invasion by Entamoeba histolytica

KS Ralston, WA Petri - Trends in parasitology, 2011 - cell.com
Entamoeba histolytica is the causative agent of amebiasis, a disease that is a major source
of morbidity and mortality in the develo** world. The potent cytotoxic activity of the parasite …

Structure of the reduced microsporidian proteasome bound by PI31-like peptides in dormant spores

N Jespersen, K Ehrenbolger, RR Winiger… - Nature …, 2022 - nature.com
Proteasomes play an essential role in the life cycle of intracellular pathogens with
extracellular stages by ensuring proteostasis in environments with limited resources. In …

Impact of genome reduction in microsporidia

N Jespersen, L Monrroy, J Barandun - Microsporidia: current advances in …, 2022 - Springer
Microsporidia represent an evolutionary outlier in the tree of life and occupy the extreme
edge of the eukaryotic domain with some of their biological features. Many of these …

[HTML][HTML] Germination of microsporidian spores: The known and unknown

Q Huang, J Chen, Q Lv, M Long, G Pan, Z Zhou - Journal of Fungi, 2023 - mdpi.com
Microsporidia are a large group of mysterious obligate intracellular eukaryotic parasites. The
microsporidian spore can survive in the absence of nutrients for years under harsh …

3-Dimensional organization and dynamics of the microsporidian polar tube invasion machinery

P Jaroenlak, M Cammer, A Davydov, J Sall… - PLoS …, 2020 - journals.plos.org
Microsporidia, a divergent group of single-celled eukaryotic parasites, harness a specialized
harpoon-like invasion apparatus called the polar tube (PT) to gain entry into host cells. The …

Identification of the Virulence Landscape Essential for Entamoeba histolytica Invasion of the Human Colon

R Thibeaux, C Weber, CC Hon, MA Dillies… - PLoS …, 2013 - journals.plos.org
Entamoeba histolytica is the pathogenic amoeba responsible for amoebiasis, an infectious
disease targeting human tissues. Amoebiasis arises when virulent trophozoites start to …

Phosphoglycerate kinase: structural aspects and functions, with special emphasis on the enzyme from Kinetoplastea

M Rojas-Pirela, D Andrade-Alviárez… - Open …, 2020 - royalsocietypublishing.org
Phosphoglycerate kinase (PGK) is a glycolytic enzyme that is well conserved among the
three domains of life. PGK is usually a monomeric enzyme of about 45 kDa that catalyses …