[HTML][HTML] Host immune response against leishmaniasis and parasite persistence strategies: A review and assessment of recent research
Leishmaniasis, a neglected parasitic disease caused by a unicellular protozoan of the
genus Leishmania, is transmitted through the bite of a female sandfly. The disease remains …
genus Leishmania, is transmitted through the bite of a female sandfly. The disease remains …
Role of chemokines in regulation of immunity against leishmaniasis
S Oghumu, CM Lezama-Dávila… - Experimental …, 2010 - Elsevier
Successful immunity to Leishmania depends on recruitment of appropriate immune effector
cells to the site of infection and chemokines play a crucial role in the process. At the same …
cells to the site of infection and chemokines play a crucial role in the process. At the same …
Immune responses during cutaneous and visceral leishmaniasis
L Kedzierski, KJ Evans - Parasitology, 2014 - cambridge.org
Leishmania are protozoan parasites spread by a sandfly insect vector and causing a
spectrum of diseases collectively known as leishmaniasis. The disease is a significant …
spectrum of diseases collectively known as leishmaniasis. The disease is a significant …
Prostaglandin E2 negatively regulates the production of inflammatory cytokines/chemokines and IL-17 in visceral leishmaniasis
A Saha, A Biswas, S Srivastav… - The Journal of …, 2014 - journals.aai.org
Persistence of intracellular infection depends on the exploitation of factors that negatively
regulate the host immune response. In this study, we elucidated the role of macrophage …
regulate the host immune response. In this study, we elucidated the role of macrophage …
Comparative transcriptomic analysis of antimony resistant and susceptible Leishmania infantum lines
JM Andrade, LO Gonçalves, DB Liarte, DA Lima… - Parasites & …, 2020 - Springer
Background One of the major challenges to leishmaniasis treatment is the emergence of
parasites resistant to antimony. To study differentially expressed genes associated with drug …
parasites resistant to antimony. To study differentially expressed genes associated with drug …
Annonaceae: breaking the wall of inflammation
Inventories of tropical forests have listed Annonaceae as one of the most diverse plant
families. For centuries, it is employed in traditional medicines to cure various pathological …
families. For centuries, it is employed in traditional medicines to cure various pathological …
[HTML][HTML] Immunotherapeutic Strategies as Potential Treatment Options for Cutaneous Leishmaniasis
Cutaneous leishmaniasis (CL), caused by protozoan parasites of the Leishmania genus, is
prevalent in tropical and subtropical regions, with important morbidity, particularly in low-to …
prevalent in tropical and subtropical regions, with important morbidity, particularly in low-to …
Immunity to visceral leishmaniasis using genetically defined live‐attenuated parasites
Leishmaniasis is a protozoan parasitic disease endemic to the tropical and subtropical
regions of the world, with three major clinical forms, self‐healing cutaneous leishmaniasis …
regions of the world, with three major clinical forms, self‐healing cutaneous leishmaniasis …
Intradermal Immunization of Leishmania donovani Centrin Knock-Out Parasites in Combination with Salivary Protein LJM19 from Sand Fly Vector Induces a Durable …
JA Fiuza, R Dey, D Davenport… - PLoS neglected …, 2016 - journals.plos.org
Background Visceral leishmaniasis (VL) is a neglected tropical disease and is fatal if
untreated. There is no vaccine available against leishmaniasis. The majority of patients with …
untreated. There is no vaccine available against leishmaniasis. The majority of patients with …
G1-4A, a Polysaccharide from Tinospora cordifolia Inhibits the Survival of Mycobacterium tuberculosis by Modulating Host Immune Responses in TLR4 Dependent …
Rapid emergence of drug resistance in Mycobacterium tuberculosis (MTB) is a major health
concern and demands the development of novel adjunct immunotherapeutic agents capable …
concern and demands the development of novel adjunct immunotherapeutic agents capable …