Connection between osteoarthritis and nitric oxide: From pathophysiology to therapeutic target

H Jiang, P Ji, X Shang, Y Zhou - Molecules, 2023 - mdpi.com
Osteoarthritis (OA), a disabling joint inflammatory disease, is characterized by the
progressive destruction of cartilage, subchondral bone remodeling, and chronic synovitis …

New refinements aim to optimize articular cartilage tissue engineering

N Schäfer, S Grässel - Nature Reviews Rheumatology, 2023 - nature.com
New refinements aim to optimize articular cartilage tissue engineering | Nature Reviews
Rheumatology Skip to main content Thank you for visiting nature.com. You are using a browser …

Hyaluronic acid–British anti-Lewisite as a safer chelation therapy for the treatment of arthroplasty-related metallosis

CC Ude, SJ Schmidt, S Laurencin, S Shah… - Proceedings of the …, 2023 - pnas.org
Cobalt-containing alloys are useful for orthopedic applications due to their low volumetric
wear rates, corrosion resistance, high mechanical strength, hardness, and fatigue …

Advanced nanofiber-based scaffolds for achilles tendon regenerative engineering

S Zhu, Z He, L Ji, W Zhang, Y Tong, J Luo… - … in Bioengineering and …, 2022 - frontiersin.org
The Achilles tendon (AT) is responsible for running, jum**, and standing. The AT injuries
are very common in the population. In the adult population (21–60 years), the incidence of …

Small molecule-mediated regenerative engineering for craniofacial and dentoalveolar bone

J Mitchell, KWH Lo - Frontiers in Bioengineering and Biotechnology, 2022 - frontiersin.org
The comprehensive reconstruction of extensive craniofacial and dentoalveolar defects
remains a major clinical challenge to this day, especially in complex medical cases involving …

Injectable biomimetic microcarriers harness synergistic effects of paracrine factors and cellular membranes to alleviate osteoarthritis

M Chen, J Wang, Y Liu, X Cui, J Liang, N Lei… - Chemical Engineering …, 2025 - Elsevier
Osteoarthritis (OA), characterized by cartilage degeneration and functional impairment,
remains a significant unmet medical need with limited therapeutic options available. While …

Stem Cell‐Based Therapies and Tissue Engineering Innovations for Tendinopathy: A Comprehensive Review of Current Strategies and Future Directions

G Augustin, JH Jeong, MK Kim, SS Hur… - Advanced …, 2024 - Wiley Online Library
Tendon diseases commonly lead to physical disability, exerting a profound impact on the
routine of affected patients. These conditions respond poorly to existing treatments …

Injectable Decorin/Gellan Gum Hydrogel Encapsulating Adipose-Derived Stem Cells Enhances Anti-Inflammatory Effect in Cartilage Injury via Autophagy Signaling

W He, Y Wu, Z Luo, G Yang, W Ye, X Chen… - Cell …, 2023 - journals.sagepub.com
Adipose-derived stem cells (ADSCs) are employed as a promising alternative in treating
cartilage injury. Regulating the inflammatory “fingerprint” of ADSCs to improve their anti …

Recent Trends in the Development of Polyphosphazenes for Bio-applications

F Chen, OR Teniola, KS Ogueri… - … and Translational Medicine, 2023 - Springer
Recent advances in biomedicine necessitate the critical and systematic review of current
trends in the development and modification of biomaterials for biomedical applications …

Animal Models of Osteoarthritis: Updated Models and Outcome Measures 2016–2023

JH Chapman, D Ghosh, S Attari, CC Ude… - Regenerative …, 2024 - Springer
Purpose Osteoarthritis (OA) is a global musculoskeletal disorder that affects primarily the
knee and hip joints without any FDA-approved disease-modifying therapies. Animal models …