Under certain conditions, RNA repeat sequences phase separate, yielding protein-free
biomolecular condensates. Importantly, RNA repeat sequences have also been implicated …

Low-complexity nucleotide repeat sequences, which are implicated in several neurological
disorders, undergo liquid–liquid phase separation (LLPS) provided the number of repeat …

Conformational dynamics of RNA plays important roles in a variety of cellular functions such
as transcriptional regulation, catalysis, scaffolding, and sensing. Recently, RNAs with low …

Biomolecular condensation lays the foundation of forming biologically important
membraneless organelles, but abnormal condensation processes are often associated with …

Intracellular aggregation of repeat expanded RNA has been implicated in many
neurological disorders. Here, we study the role of biomolecular condensates on irreversible …

Messenger RNA (mRNA) encapsulated in lipid nanoparticles (LNPs) represents a cutting-
edge delivery technology that played a pivotal role during the COVID-19 pandemic and in …

Biomolecular condensates are membraneless organelles formed via phase separation of
macromolecules, typically consisting of bond-forming “stickers” connected by flexible …

We present a theoretical model for predicting the phase behavior of polymer solutions in
which phase separation competes with oligomerization. Specifically, we consider scenarios …

In many biopolymer solutions, attractive interactions that stabilize finite-sized clusters at low
concentrations also promote phase separation at high concentrations. Here we study a …

Biomolecular condensates are membraneless organelles formed via phase separation of
macromolecules, typically consisting of bond-forming “stickers” connected by flexible …