The adaptive immune system and associated inflammation are vital in surveillance and host
protection against internal and external threats, but can secondarily damage host tissues …

Inflammation is a cellular response to factors that challenge the homeostasis of cells and
tissues. Cell-associated and soluble pattern-recognition receptors, eg Toll-like receptors …

Age-related macular degeneration (AMD) is the leading cause of legal blindness in the
industrialized world. AMD is characterized by accumulation of extracellular deposits, namely …

Neovascular age-related macular degeneration (AMD) has undergone substantial break-
throughs in diagnostic as well as therapeutic respect, with optical coherence tomography …

Age-related macular degeneration (AMD) is the most common cause of blindness among
the elderly in the developed world. While treatment is effective for the neovascular or “wet” …

Ocular inflammation is a defining feature of sight threating diseases and its dysregulation
can catalyze and or propagate ocular neurodegenerative maladies such as age-related …

Purpose: To study the levels of complement activation in different disease stages of AMD
and the influence of genetic polymorphisms in complement genes. Methods: We included …

Lutein is concentrated in the primate retina, where together with zeaxanthin it forms the
macular pigment. Traditionally lutein is characterized by its blue light filtering and anti …

Complement is the major humoral component of the innate immune system. It recognizes
pathogen-and damage-associated molecular patterns, and initiates the immune response in …

Age-related macular degeneration (AMD) is a common cause of visual loss in the elderly,
with increasing prevalence due to increasing life expectancy. While the introduction of anti …