Nowadays, diet and specific dietary supplements are seen as potential adjuvants to prevent
different chronic diseases, including cancer, or to ameliorate pharmacological therapies …

Prostate and breast cancer are the two cancers with the highest incidence in men and
women, respectively. Here, we focus on the known biology of acquired resistance to …

On Thursday, January2, 1997, Dr. HerbertSoule, the scientist who developed the MCF-7
breast cancer cell line, died. At the time, we were in the process of writingthis tributeto …

Quercetin is a dietary flavonoid which exerts anti-oxidant, anti-inflammatory and anti-cancer
properties. In this study, we investigated the anti-proliferative effect of quercetin in two breast …

The human breast undergoes a complete series of changes from intrauterine life to
senescence. These changes can be divided into two distinct phases; the developmental …

In 1958, Lerner and coworkers published their landmark paper on the pharmacological
properties of the first nonsteroidal antiestrogen ethamoxytriphetol or MER-25 (fig. 1). Lerner …

Background: A major challenge in cancer chemotherapy has been develo** safe and
clinically efficacious chemotherapeutic agents. With its low toxicity profile, curcumin …

Abstract Using an Affymetrix 10K SNP array to screen for gene copy number changes in
breast cancer, we detected a single-gene amplification of the ESR1 gene, which encodes …

Various oestrogen responsive reporter genes and vectors expressing truncated or chimeric
human oestrogen receptors (hER) containing either of the two independent hER …

Breast cancer, the most frequent spontaneousmalignancy diagnosed in women in the
Western world, isa classical model of hormone dependent malignancy. Thereis substantial …