Antibiotic resistance is a global health emergency, with resistance detected to all antibiotics
currently in clinical use and only a few novel drugs in the pipeline. Understanding the …

Antimicrobial resistance (AMR) is tracked most closely in clinical settings and high-income
countries. However, resistant organisms thrive globally and are transmitted to and from …

Acinetobacter baumannii is a Gram-negative ESKAPE microorganism that poses a threat to
public health by causing severe and invasive (mostly nosocomial) infections linked with high …

Acinetobacter baumannii-calcoaceticus complex is the most commonly identified species in
the genus Acinetobacter and it accounts for a large percentage of nosocomial infections …

Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …

The use of life-saving antibiotics has long been plagued by the ability of pathogenic bacteria
to acquire and develop an array of antibiotic resistance mechanisms. The sum of these …

Background Following the discovery and emergence of the plasmid-mediated colistin
resistance gene, mcr-1, the Chinese government formally banned colistin as an animal …

The antibacterial agents currently in clinical development are predominantly derivatives of
well-established antibiotic classes and were selected to address the class-specific …

The expanding use of antimicrobials in livestock is an important contributor to the worldwide
rapid increase in antimicrobial resistance (AMR). However, large-scale studies on AMR in …

The tetracycline antibiotic class has acquired new valuable members due to the optimisation
of the chemical structure. The first modern tetracycline introduced into therapy was …