Aberrant brain network connectivity in presymptomatic and manifest Huntington's disease: A systematic review
Resting‐state functional magnetic resonance imaging (rs‐fMRI) has the potential to shed
light on the pathophysiological mechanisms of Huntington's disease (HD), paving the way to …
light on the pathophysiological mechanisms of Huntington's disease (HD), paving the way to …
Cognitive and social cognition deficits in Huntington's disease differ between the prodromal and the manifest stages of the condition: A sco** review of recent …
M Cavallo, A Sergi, M Pagani - British Journal of Clinical …, 2022 - Wiley Online Library
Objective Huntington's disease (HD) is a dramatic neurodegenerative disorder
encompassing severe motor symptoms coupled to significant cognitive and social cognition …
encompassing severe motor symptoms coupled to significant cognitive and social cognition …
Wayfinding and path integration deficits detected using a virtual reality mobile app in patients with traumatic brain injury
The ability to navigate is supported by a wide network of brain areas which are particularly
vulnerable to disruption brain injury, including traumatic brain injury (TBI). Wayfinding and …
vulnerable to disruption brain injury, including traumatic brain injury (TBI). Wayfinding and …
Cilia in the striatum mediate timing-dependent functions
W Alhassen, S Alhassen, J Chen, RV Monfared… - Molecular …, 2023 - Springer
Almost all brain cells contain cilia, antennae-like microtubule-based organelles. Yet, the
significance of cilia, once considered vestigial organelles, in the higher-order brain functions …
significance of cilia, once considered vestigial organelles, in the higher-order brain functions …
Spatial memory in Huntington's disease: A comparative review of human and animal data
To improve the translational predictability of treatment strategies for Huntington's disease
(HD), sensitive and analogous cognitive outcomes are needed across HD animal models …
(HD), sensitive and analogous cognitive outcomes are needed across HD animal models …
Humanized dopamine D4.7 receptor male mice display risk‐taking behavior and deficits of social recognition and working memory in light/dark‐dependent manner
The dopamine D4 receptor 7‐repeat allele (D4. 7R) has been linked with psychiatric
disorders such as attention‐deficit–hyperactivity disorder, autism, and schizophrenia …
disorders such as attention‐deficit–hyperactivity disorder, autism, and schizophrenia …
[HTML][HTML] Hippocampal morphology in Huntington's disease, implications for plasticity and pathogenesis: The IMAGE-HD study
While striatal changes in Huntington's Disease (HD) are well established, few studies have
investigated changes in the hippocampus, a key neuronal hub. Using MRI scans obtained …
investigated changes in the hippocampus, a key neuronal hub. Using MRI scans obtained …
'Real-life'hippocampal-dependent spatial memory impairments in Huntington's disease
Hippocampal-dependent spatial memory impairments are seen in Huntington's disease
animal models. Similar impairments were recently reported in Huntington's disease …
animal models. Similar impairments were recently reported in Huntington's disease …
Hippocampal and striatal volumes correlate with spatial memory impairment in Huntington's disease
Y Glikmann‐Johnston, EC Mercieca… - Journal of …, 2021 - Wiley Online Library
Spatial memory impairments are observed in people with Huntington's disease (HD),
however, the domain of spatial memory has received little focus when characterizing the …
however, the domain of spatial memory has received little focus when characterizing the …
Pervasive autobiographical memory impairments in Huntington's disease
Autobiographical memory dysfunction is a pervasive feature of neurodegenerative
disorders, but less is known about the integrity of autobiographical memory in Huntington's …
disorders, but less is known about the integrity of autobiographical memory in Huntington's …