The important life-supporting role of hydrogen sulfide (H2S) has evolved from bacteria to
plants, invertebrates, vertebrates, and finally to mammals. Over the centuries, however, H2S …

Vascular smooth muscle cells (VSMCs) are the fundamental component of the medial layer
of arteries and are essential for arterial physiology and pathology. It is becoming …

Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

Hydrogen sulfide (H2S) is a gaseous mediator synthesized from cysteine by cystathionine γ
lyase (CSE) and other naturally occurring enzymes. Pharmacological experiments using …

It has been known for more than 60 years, and suspected for over 100, that alveolar hypoxia
causes pulmonary vasoconstriction by means of mechanisms local to the lung. For the last …

The discovery of the sensory nature of the carotid body dates back to the beginning of the
20th century. Following these seminal discoveries, research into carotid body mechanisms …

Global warming and local eutrophication simultaneously lower oxygen (O2) saturation and
increase biological O2 demands to cause deoxygenation. Tropical shallow waters, and their …

Hydrogen sulfide (H 2 S) is the most recent endogenous gasotransmitter that has been
reported to serve many physiological and pathological functions in different tissues. Studies …

The mammalian brain is highly vulnerable to oxygen deprivation, yet the mechanism
underlying the brain's sensitivity to hypoxia is incompletely understood. Hypoxia induces …

Intracellular viscosity is an essential microenvironmental parameter and H2S is a critical
gaseous signaling molecule, which are both related to various physiological processes. It is …