Fluorinated molecules have a wide range of applications and are used as medicines,
agrochemicals and refrigerants and in smartphone liquid crystal displays, photovoltaic solar …

During the past decades, synthetic organic chemistry discovered that directing group
assisted C–H activation is a key tool for the expedient and siteselective construction of C–C …

C–H activation has surfaced as an increasingly powerful tool for molecular sciences, with
notable applications to material sciences, crop protection, drug discovery, and …

Copper is one of the most abundant and less toxic transition metals. Nature takes advantage
of the bioavailability and rich redox chemistry of Cu to carry out oxygenase and oxidase …

We disclose a Bi-catalyzed C–H trifluoromethylation of (hetero) arenes using CF3SO2Cl
under light irradiation. The catalytic method permits the direct functionalization of various …

Incorporation of the CF3 group into arenes has found increasing importance in drug
discovery. Herein, we report the first photoredox‐catalyzed cross‐coupling of aryl …

Owing to the market competitiveness and urgent societal need, an optimum speed of drug
discovery is an important criterion for successful implementation. Despite the rapid ascent of …

A copper-catalyzed three-component reaction of cyclobutanone oxime esters and 1, 3-
enynes in the presence of TMSCN or TMSCF3 has been developed. This mild protocol …

The unique properties of the fluorine-containing compounds and their widespread
applications raise the demand for dependable synthetic methods on the precise introduction …

Transition metal-catalyzed direct functionalization of C–H bonds has recently emerged as a
powerful strategy for the construction of carbon–carbon and carbon–heteroatom bonds …