Mechanisms governing autophagosome biogenesis

H Nakatogawa - Nature reviews Molecular cell biology, 2020 - nature.com
Autophagosomes are double-membrane vesicles newly formed during autophagy to engulf
a wide range of intracellular material and transport this autophagic cargo to lysosomes (or …

Autophagy and autophagy-related proteins in cancer

X Li, S He, B Ma - Molecular cancer, 2020 - Springer
Autophagy, as a type II programmed cell death, plays crucial roles with autophagy-related
(ATG) proteins in cancer. Up to now, the dual role of autophagy both in cancer progression …

Emerging roles of ATG proteins and membrane lipids in autophagosome formation

T Nishimura, SA Tooze - Cell discovery, 2020 - nature.com
Autophagosome biogenesis is a dynamic membrane event, which is executed by the
sequential function of autophagy-related (ATG) proteins. Upon autophagy induction, a cup …

Guidelines for the use and interpretation of assays for monitoring autophagy

DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin… - Autophagy, 2016 - escholarship.org
Many researchers, especially those new to the field, need to determine which criteria are
essential for demonstrating autophagy, either for the purposes of their own research, or in …

Autophagy: an essential degradation program for cellular homeostasis and life

Y Chun, J Kim - Cells, 2018 - mdpi.com
Autophagy is a lysosome-dependent cellular degradation program that responds to a variety
of environmental and cellular stresses. It is an evolutionarily well-conserved and essential …

Mechanisms of autophagy initiation

JH Hurley, LN Young - Annual review of biochemistry, 2017 - annualreviews.org
Autophagy is the process of cellular self-eating by a double-membrane organelle, the
autophagosome. A range of signaling processes converge on two protein complexes to …

The machinery of macroautophagy

Y Feng, D He, Z Yao, DJ Klionsky - Cell research, 2014 - nature.com
Autophagy is a primarily degradative pathway that takes place in all eukaryotic cells. It is
used for recycling cytoplasm to generate macromolecular building blocks and energy under …

Historical landmarks of autophagy research

Y Ohsumi - Cell research, 2014 - nature.com
The year of 2013 marked the 50th anniversary of C de Duve's coining of the term
“autophagy” for the degradation process of cytoplasmic constituents in the …

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif… - autophagy, 2021 - Taylor & Francis
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

[HTML][HTML] Guidelines for the use and interpretation of assays for monitoring autophagy 1

DJ Klionsky, AK Abdel-Aziz, S Abdelfatah… - …, 2021 - pmc.ncbi.nlm.nih.gov
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …