Growing evidence has shown that brain activity at rest slowly wanders through a repertoire
of different states, where whole-brain functional connectivity (FC) temporarily settles into …

Introduction Health inequalities are recognised as a public health issue worldwide, but only
a few countries have developed national strategies to monitor and reduce them. Despite its …

Gene-environment interactions drive experience-dependent changes in the brain that alter
cognition, emotion and behaviour. Positive engagement with the environment, through novel …

Previous studies have shown an association between cognitive decline and white matter
integrity in aging. This led to the formulation of a “disconnection hypothesis” in the aging …

Alzheimer's disease (AD) is a frequently observed, irreversible brain function disorder
among elderly individuals. Resting-state functional magnetic resonance imaging (rs-fMRI) …

The fourth edition of the highly acclaimed Principles and Practice of Geriatric Medicine
provides an account of the fundamental changes associated with ageing, which are …

Cognitive Reserve (CR) designates the brain's capacity to actively cope with insults through
a more efficient use of its resources/networks. It was proposed in order to explain the …

Numerous studies have suggested that educational history, as a proxy measure of active
cognitive reserve, protects against age-related cognitive decline and risk of dementia …

Few studies have examined the influence of a low level of schooling on age-related
cognitive decline in countries with wide social and economic inequalities by using the …

Background: Older adults are at a greater risk for contracting and experiencing severe
illness from COVID-19 and may be further affected by pandemic-related precautions (eg …