Ferroptosis regulation through Nrf2 and implications for neurodegenerative diseases

Y **ang, X Song, D Long - Archives of Toxicology, 2024 - Springer
This article provides an overview of the background knowledge of ferroptosis in the nervous
system, as well as the key role of nuclear factor E2-related factor 2 (Nrf2) in regulating …

Pharmacological modulation of Nrf2/HO-1 signaling pathway as a therapeutic target of Parkinson's disease

Y Wang, L Gao, J Chen, Q Li, L Huo, Y Wang… - Frontiers in …, 2021 - frontiersin.org
Parkinson's disease (PD) is a complex neurodegenerative disorder featuring both motor and
nonmotor symptoms associated with a progressive loss of dopaminergic neurons in the …

The effects of bioactive components from the rhizome of gastrodia elata blume (Tianma) on the characteristics of Parkinson's disease

C Lu, S Qu, Z Zhong, H Luo, SS Lei… - Frontiers in …, 2022 - frontiersin.org
Parkinson's disease (PD) is an age-related chronic neurodegenerative disease caused by
the death and degeneration of dopaminergic neurons in the substantia nigra of the midbrain …

Underlying mechanisms behind the neuroprotective effect of vanillic acid against diabetes‐associated cognitive decline: An in vivo study in a rat model

S Ghaderi, P Gholipour, A Komaki… - Phytotherapy …, 2024 - Wiley Online Library
Hippocampal synaptic dysfunction, oxidative stress, neuroinflammation, and neuronal loss
play critical roles in the pathophysiology of diabetes‐associated cognitive decline (DACD) …

Protective effects of vanillic acid on autistic-like behaviors in a rat model of maternal separation stress: Behavioral, electrophysiological, molecular and …

M Farzan, M Farzan, H Amini-Khoei, M Shahrani… - International …, 2023 - Elsevier
Compounds derived from herbs exhibit a range of biological properties, including anti-
inflammatory, antioxidant, and neuroprotective properties. However, the exact mechanism of …

GSK-3β-mediated regulation of Nrf2/HO-1 signaling as a new therapeutic approach in the treatment of movement disorders

D Soni, P Kumar - Pharmacological Reports, 2022 - Springer
Movement disorders are neurological conditions characterized by involuntary motor
movements, such as dystonia, ataxia, chorea myoclonus, tremors, Huntington's disease …

[HTML][HTML] Dendrobium species regulate energy homeostasis in neurodegenerative diseases: a review

F Wang, J Wan, Y Liao, S Liu, Y Wei… - Food Science and Human …, 2023 - Elsevier
Brain energy homeostasis is a vital physiological function in maintaining a balanced internal
metabolic environment. The impairment of energy homeostasis is recognized as a key …

Neuroprotective effect of maresin-1 in rotenone-induced Parkinson's disease in rats: The putative role of the JAK/STAT pathway

SA Khodir, EM Sweed, MA Faried… - Neurochemical …, 2025 - Springer
Exposure to rotenone results in similar pathophysiological features as Parkinson's disease.
Inflammation and oxidative stress are essential to PD pathogenesis. Maresin-1 has potent …

The effects of gallic acid and vagotomy on motor function, intestinal transit, brain electrophysiology and oxidative stress alterations in a rat model of Parkinson's …

E Sheikhpour, SA Mard, Y Farbood, K Bavarsad… - Life Sciences, 2023 - Elsevier
Abstract Introduction The neuropathology of Parkinson's disease (PD) is complex and affects
multiple systems of the body beyond the central nervous system. This study examined the …

Urine biomarkers discovery by metabolomics and machine learning for Parkinson's disease diagnoses

X Wang, X Hao, J Yan, J Xu, D Hu, F Ji, T Zeng… - Chinese Chemical …, 2023 - Elsevier
Parkinson's disease (PD) is a complex neurological disorder that typically worsens with age.
A wide range of pathologies makes PD a very heterogeneous condition, and there are …