The discovery that brain tissue could potentially be salvaged from ischaemia due to stroke,
has led to major advances in the development of therapies for ischemic stroke. In this …

Despite the availability of thrombolytic and endovascular therapy for acute ischemic stroke,
many patients are ineligible due to delayed hospital arrival. The identification of factors …

Abstract Background and Purpose Acute ischemic stroke due to large vessel occlusion (AIS‐
LVO) is a major cause of functional dependence. Collateral status (CS) is an important …

For alleviating ischemic reperfusion injury, reasonable design mimic multi-functional
nanozyme can simultaneously capture ROS and inhibit inflammatory factors, which plays an …

Arterial collateralization, as determined by leptomeningeal anastomoses or pial collateral
vessels, is a well‐established vital player in cerebral blood flow restoration and neurological …

CT perfusion images can be rapidly obtained on all modern CT scanners and easily
incorporated into an acute stroke imaging protocol. Here we discuss the technique of CT …

Purpose The recommendation strength of the guidelines for mechanical thrombectomy
among patients with large pre-treatment core infarct is weak. We evaluated the safety and …

Objective: Advanced neuroimaging has proved to be pivotal in the management of acute
ischemic stroke. The use of CT perfusion (CTP) core and penumbra parameters to predict …

It has been 40 years since the ischemic penumbra was first conceptualized through work on
animal models. The topography of penumbra has been portrayed as an infarcted core …

Objective To construct a stable rat portal vein thrombosis (PVT) model and explore the time
window of urokinase thrombolytic therapy on this basis. Methods Constructing a rat PVT …