[HTML][HTML] Hallmarks of regeneration

KD Poss, EM Tanaka - Cell stem cell, 2024 - cell.com
Regeneration is a heroic biological process that restores tissue architecture and function in
the face of day-to-day cell loss or the aftershock of injury. Capacities and mechanisms for …

Compartmentalization, cooperation, and communication: The 3Cs of Hepatocyte zonation

N Porat-Shliom - Current Opinion in Cell Biology, 2024 - Elsevier
The unique architecture of the liver allows for spatial compartmentalization of its functions,
also known as liver zonation. In contrast to organelles and cells, this compartment is devoid …

A developmental biliary lineage program cooperates with Wnt activation to promote cell proliferation in hepatoblastoma

PV Wu, M Fish, FK Hazard, C Zhu, S Vennam… - Nature …, 2024 - nature.com
Cancers evolve not only through the acquisition and clonal transmission of somatic
mutations but also by epigenetic mechanisms that modify cell phenotype. Here, we use …

[HTML][HTML] Integrating the study of polyploidy across organisms, tissues, and disease

JP Morris, T Baslan, DE Soltis, PS Soltis… - Annual review of …, 2024 - pmc.ncbi.nlm.nih.gov
Polyploidy is a cellular state containing more than two complete chromosome sets. It has
largely been studied as a discrete phenomenon in either organismal, tissue, or disease …

Reduced liver damage and fibrosis with combined SCD Probiotics and intermittent fasting in aged rat

HT Teker, T Ceylani, S Keskin… - Journal of Cellular …, 2024 - Wiley Online Library
This study aimed to examine the impact of SCD Probiotics supplementation on liver
biomolecule content and histological changes during a 30‐day intermittent fasting (IF) …

Integrating the Study of Polyploidy Across Organisms, Tissues, and Disease

JP Morris 4th, T Baslan, DE Soltis… - Annual Review of …, 2024 - annualreviews.org
Polyploidy is a cellular state containing more than two complete chromosome sets. It has
largely been studied as a discrete phenomenon in either organismal, tissue, or disease …

[HTML][HTML] β-hydroxybutyrate: a crucial therapeutic target for diverse liver diseases

K Li, WH Wang, J Wu, W **ao - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Abstract β-hydroxybutyrate (β-HB), the most abundant ketone body, is produced primarily in
the liver and acts as a substitute energy fuel to provide energy to extrahepatic tissues in the …

[HTML][HTML] Non-specific recognition of histone modifications by H3K9bhb antibody

T Tsusaka, JA Oses-Prieto, C Lee, BC DeFelice… - Iscience, 2023 - cell.com
Ketone bodies are short-chain fatty acids produced in the liver during periods of limited
glucose availability that provide an alternative energy source for the brain, heart, and …

The hepatic clock synergizes with HIF-1α to regulate nucleotide availability during liver damage repair

L Peng, S **ang, T Wang, M Yang, Y Duan, X Ma… - Nature …, 2025 - nature.com
Nucleotide availability is crucial for DNA replication and repair; however, the coordinating
mechanisms in vivo remain unclear. Here, we show that the circadian clock in the liver …

IDSL. GOA: gene ontology analysis for interpreting metabolomic datasets

P Mahajan, O Fiehn, D Barupal - Scientific Reports, 2024 - nature.com
Biological interpretation of metabolomic datasets often ends at a pathway analysis step to
find the over-represented metabolic pathways in the list of statistically significant …