Understanding vertebrate immunity through comparative immunology

T Boehm - Nature Reviews Immunology, 2024 - nature.com
Evolutionary immunology has entered a new era. Classical studies, using just a handful of
model animal species, combined with clinical observations, provided an outline of how …

The Current Status and Development Forecasts of Vaccines for Aquaculture and its Effects on Bacterial and Viral Diseases

EM Mkulo, B Wang, K Amoah, Y Huang, C Jia… - Microbial …, 2024 - Elsevier
The aquaculture sector predicts protein-rich meals by 2040 and has experienced significant
economic shifts since 2000. However, challenges emanating from disease control …

Varying conjunctival immune response adaptations of house finch populations to a rapidly evolving bacterial pathogen

N Kuttiyarthu Veetil, AE Henschen, DM Hawley… - Frontiers in …, 2024 - frontiersin.org
Pathogen adaptations during host-pathogen co-evolution can cause the host balance
between immunity and immunopathology to rapidly shift. However, little is known in natural …

Peripheral inflammation-induced changes in songbird brain gene expression: 3'mRNA transcriptomic approach

NK Veetil, HC de Oliveira, M Gomez-Samblas… - Developmental & …, 2024 - Elsevier
Species-specific neural inflammation can be induced by profound immune signalling from
periphery to brain. Recent advances in transcriptomics offer cost-effective approaches to …

Positive selection on mammalian immune genes—effects of gene function and selective constraint

M Nandakumar, M Lundberg… - … Biology and Evolution, 2025 - academic.oup.com
Genome-wide analyses of various taxa have repeatedly shown that immune genes are
important targets of positive selection. However, little is known about what factors determine …

Natural selection directing molecular evolution in vertebrate viral sensors

B Melepat, T Li, M Vinkler - Developmental & Comparative Immunology, 2024 - Elsevier
Diseases caused by pathogens contribute to molecular adaptations in host immunity. Variety
of viral pathogens challenging animal immunity can drive positive selection diversifying …

AMPed up immunity: 418 whole genomes reveal intraspecific diversity of koala antimicrobial peptides

C Petrohilos, E Peel, LW Silver, K Belov, CJ Hogg - Immunogenetics, 2025 - Springer
Characterising functional diversity is a vital element to understanding a species' immune
function, yet many immunogenetic studies in non-model organisms tend to focus on only …

Assessing immune phenotypes using simple proxy measures: promise and limitations

AE Downie, RS Barre, A Robinson, J Yang… - Discovery …, 2024 - academic.oup.com
The study of immune phenotypes in wild animals is beset by numerous methodological
challenges, with assessment of detailed aspects of phenotype difficult to impossible. This …

Local chicken breeds exhibit abundant TCR-V segments but similar repertoire diversity

C Liang, L Sun, Y Zhu, J Wu, A Zhao, T Huang… - Developmental & …, 2024 - Elsevier
The thymus-derived lymphocytes of jawed vertebrates have four T-cell receptor (TCR)
chains that play a significant role in immunity. As chickens have commercial value, their …

The cytokine genes of Oncorhynchus masou formosanus include a defective interleukin-4/13A gene

YH Yen, SY Yang, JC Gwo, SD Fugmann - … & Comparative Immunology, 2024 - Elsevier
Oncorhynchus masou formosanus (Formosa landlocked salmon) is a critically endangered
salmonid fish endemic to Taiwan. To begin to understand how its drastic change in lifestyle …