Bioactivity assessment and toxicity of crocin: a comprehensive review

SH Alavizadeh, H Hosseinzadeh - Food and chemical toxicology, 2014 - Elsevier
Since ancient times, saffron, the dried stigma of the plant Crocus sativus L. has been
extensively used as a spice and food colorant; in folk medicine it has been reputed to be …

Nanoencapsulation of carotenoids within lipid-based nanocarriers

H Rostamabadi, SR Falsafi, SM Jafari - Journal of controlled release, 2019 - Elsevier
Carotenoids, as promising functional components in human diet, are gaining immense
importance todays. Apart from their pivotal importance in photosynthetic organisms or as …

[HTML][HTML] A comprehensive review of the pharmacological potential of Crocus sativus and its bioactive apocarotenoids

SI Bukhari, M Manzoor, MK Dhar - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Crocus sativus is an herbaceous plant that belongs to family Iridaceae. It is commonly
known as saffron and has been used for medicinal purposes since many centuries in India …

Recent Advances on the Anticancer Properties of Saffron (Crocus sativus L.) and Its Major Constituents

A Lambrianidou, F Koutsougianni, I Papapostolou… - Molecules, 2020 - mdpi.com
Cancer is the second leading cause of death globally with an estimated 9.6 million deaths in
2018 and a sustained rise in its incidence in both develo** and developed countries …

Pharmacokinetic properties of saffron and its active components

A Hosseini, BM Razavi, H Hosseinzadeh - European Journal of Drug …, 2018 - Springer
Saffron as a medicinal plant has many therapeutic effects. Phytochemical studies have
reported that saffron is composed of at least four active ingredients which include crocin …

Crocin-loaded nanocarriers; approaches and applications

S Tavasoli, Z Borjizadeh, A Anvar, H Ahari… - Current Opinion in Food …, 2023 - Elsevier
Crocin (CR), an important carotenoid in saffron, is known for its significant biological
benefits. Despite its therapeutic potential, there are some challenges that hamper its use as …

Crocetin and crocin from saffron in cancer chemotherapy and chemoprevention

A Colapietro, A Mancini… - Anti-Cancer Agents …, 2019 - ingentaconnect.com
Introduction: Cancer is a disorder which has a powerful impact on the quality life and life
expectancy despite the increase in drugs and treatments available for cancer patients …

[HTML][HTML] Anticarcinogenic effect of saffron (Crocus sativus L.) and its ingredients

S Samarghandian, A Borji - Pharmacognosy research, 2014 - ncbi.nlm.nih.gov
Conventional and newly emerging treatment procedures such as chemotherapy, catalytic
therapy, photodynamic therapy and radiotherapy have not succeeded in reversing the …

An updated comprehensive review on vitamin A and carotenoids in breast cancer: mechanisms, genetics, assessment, current evidence, and future clinical …

JA Kim, JH Jang, SY Lee - Nutrients, 2021 - mdpi.com
Vitamin A and carotenoids are fat-soluble micronutrients that play important role as powerful
antioxidants modulating oxidative stress and cancer development. Breast cancer is the most …

Improvement of crocin stability by biodegradeble nanoparticles of chitosan-alginate

S Rahaiee, SA Shojaosadati, M Hashemi… - International Journal of …, 2015 - Elsevier
This study aimed to improve the stability of crocin, a saffron carotenoid, encapsulating into
chitosan (Cs)-sodium alginate (Alg) nanoparticles prepared by a modified ionic gelation …