Photodynamic therapy: Innovative approaches for antibacterial and anticancer treatments

M Kolarikova, B Hosikova, H Dilenko… - Medicinal Research …, 2023 - Wiley Online Library
Photodynamic therapy is an alternative treatment mainly for cancer but also for bacterial
infections. This treatment dates back to 1900 when a German medical school graduate …

The role of tumor microenvironment in cancer metastasis: Molecular mechanisms and therapeutic opportunities

CM Neophytou, M Panagi, T Stylianopoulos… - Cancers, 2021 - mdpi.com
Simple Summary Metastasis, the process by which cancer cells escape primary tumor site
and colonize distant organs, is responsible for most cancer-related deaths. The tumor …

An overview of coumarin as a versatile and readily accessible scaffold with broad-ranging biological activities

F Annunziata, C Pinna, S Dallavalle… - International Journal of …, 2020 - mdpi.com
Privileged structures have been widely used as an effective template for the research and
discovery of high value chemicals. Coumarin is a simple scaffold widespread in Nature and …

Nanotechnology for boosting cancer immunotherapy and remodeling tumor microenvironment: the horizons in cancer treatment

S Gao, X Yang, J Xu, N Qiu, G Zhai - ACS nano, 2021 - ACS Publications
Immunotherapy that harnesses the human immune system to fight cancer has received
widespread attention and become a mainstream strategy for cancer treatment. Cancer …

Current perspectives and trend of nanomedicine in cancer: A review and bibliometric analysis

Z Pei, S Chen, L Ding, J Liu, X Cui, F Li, F Qiu - Journal of Controlled …, 2022 - Elsevier
The limitations of traditional cancer treatments are driving the creation and development of
new nanomedicines. At present, with the rapid increase of research on nanomedicine in the …

Targeting glucose metabolism to suppress cancer progression: prospective of anti-glycolytic cancer therapy

AF Abdel-Wahab, W Mahmoud, RM Al-Harizy - Pharmacological research, 2019 - Elsevier
Most solid tumor cells adapt to their heterogeneous microenvironment by depending largely
on aerobic glycolysis for energy production, a phenomenon called the Warburg effect, which …

Nanotechnology for multimodal synergistic cancer therapy

W Fan, B Yung, P Huang, X Chen - Chemical reviews, 2017 - ACS Publications
The complexity, diversity, and heterogeneity of tumors seriously undermine the therapeutic
potential of treatment. Therefore, the current trend in clinical research has gradually shifted …

Advances in application of azobenzene as a trigger in biomedicine: Molecular design and spontaneous assembly

HB Cheng, S Zhang, J Qi, XJ Liang… - Advanced …, 2021 - Wiley Online Library
Azobenzene is a well‐known derivative of stimulus‐responsive molecular switches and has
shown superior performance as a functional material in biomedical applications. The results …

Current status and prospects of MOFs in controlled delivery of Pt anticancer drugs

J Chen, Z Zhang, J Ma, A Nezamzadeh-Ejhieh… - Dalton …, 2023 - pubs.rsc.org
Cancer has become the second leading reason for death in the world. Still, cancer therapy
development is exceptionally challenging because the tumor microenvironment is very …

Targeting the bicarbonate transporter SLC4A4 overcomes immunosuppression and immunotherapy resistance in pancreatic cancer

F Cappellesso, MP Orban, N Shirgaonkar, E Berardi… - Nature Cancer, 2022 - nature.com
Solid tumors are generally characterized by an acidic tumor microenvironment (TME) that
favors cancer progression, therapy resistance and immune evasion. By single-cell RNA …