[HTML][HTML] Ageing–oxidative stress, PTMs and disease
Post-translational modifications (PTMs) have been proposed as a link between the oxidative
stress-inflammation-ageing trinity, thereby affecting several hallmarks of ageing …
stress-inflammation-ageing trinity, thereby affecting several hallmarks of ageing …
Single-cell analyses of aging, inflammation and senescence
Single-cell gene expression (transcriptomics) data are becoming robust and abundant, and
are increasingly used to track organisms along their life-course. This allows investigation …
are increasingly used to track organisms along their life-course. This allows investigation …
Healthspan Maintenance and Prevention of Parkinson's-like Phenotypes with Hydroxytyrosol and Oleuropein Aglycone in C. elegans
G Brunetti, G Di Rosa, M Scuto, M Leri… - International journal of …, 2020 - mdpi.com
Numerous studies highlighted the beneficial effects of the Mediterranean diet (MD) in
maintaining health, especially during ageing. Even neurodegeneration, which is part of the …
maintaining health, especially during ageing. Even neurodegeneration, which is part of the …
Healthspan Enhancement by Olive Polyphenols in C. elegans Wild Type and Parkinson's Models
G Di Rosa, G Brunetti, M Scuto… - International Journal of …, 2020 - mdpi.com
Parkinson's disease (PD) is the second most prevalent late-age onset neurodegenerative
disorder, affecting 1% of the population after the age of about 60 years old and 4% of those …
disorder, affecting 1% of the population after the age of about 60 years old and 4% of those …
[HTML][HTML] Cerebral small vessel disease alters neurovascular unit regulation of microcirculation integrity involved in vascular cognitive impairment
Q Yang, X Wei, B Deng, Z Chang, D **, Y Huang… - Neurobiology of …, 2022 - Elsevier
Cerebral small vessel disease (CSVD) is a generic term used for intracranial vascular
disorders caused by the structural changes of cerebral microvessels, including the small …
disorders caused by the structural changes of cerebral microvessels, including the small …
Ranking biomarkers of aging by citation profiling and effort scoring
A Hartmann, C Hartmann, R Secci, A Hermann… - Frontiers in …, 2021 - frontiersin.org
Aging affects most living organisms and includes the processes that reduce health and
survival. The chronological and the biological age of individuals can differ remarkably, and …
survival. The chronological and the biological age of individuals can differ remarkably, and …
Ligusticum chuanxiong Hort as a medicinal and edible plant foods: Antioxidant, anti-aging and neuroprotective properties in Caenorhabditis elegans
Y Qin, F Chen, Z Tang, H Ren, Q Wang… - Frontiers in …, 2022 - frontiersin.org
Ligusticum chuanxiong Hort.(CX) is a medicinal and edible plant including a variety of active
substances, which may be an available resource for the treatment of related diseases. To …
substances, which may be an available resource for the treatment of related diseases. To …
Are we ill because we age?
Growing elderly populations, sometimes referred to as gray (or silver) tsunami, are an
increasingly serious health and socioeconomic concern for modern societies. Science has …
increasingly serious health and socioeconomic concern for modern societies. Science has …
Improvements to healthspan through environmental enrichment and lifestyle interventions: where are we now?
NJ Queen, QN Hassan, L Cao - Frontiers in Neuroscience, 2020 - frontiersin.org
Environmental enrichment (EE) is an experimental paradigm that is used to explore how a
complex, stimulating environment can impact overall health. In laboratory animal …
complex, stimulating environment can impact overall health. In laboratory animal …
Vascular aging detected by peripheral endothelial dysfunction is associated with ecg‐derived physiological aging
Background An artificial intelligence algorithm that detects age using the 12‐lead ECG has
been suggested to signal “physiologic age.” This study aimed to investigate the association …
been suggested to signal “physiologic age.” This study aimed to investigate the association …