Oxidative stress mediated mitochondrial and vascular lesions as markers in the pathogenesis of Alzheimer disease

G Aliev, M Priyadarshini, V P. Reddy… - Current medicinal …, 2014 - benthamdirect.com
Mitochondrial dysfunction plausibly underlies the aging-associated brain degeneration.
Mitochondria play a pivotal role in cellular bioenergetics and cell-survival. Oxidative stress …

Brain mitochondria as a primary target in the development of treatment strategies for Alzheimer disease

G Aliev, HH Palacios, B Walrafen, AE Lipsitt… - The international journal …, 2009 - Elsevier
Alzheimer's disease (AD) and cerebrovascular accidents are two leading causes of age-
related dementia. Increasing evidence supports the idea that chronic hypoperfusion is …

Nitric oxide as an initiator of brain lesions during the development of Alzheimer disease

G Aliev, HH Palacios, AE Lipsitt, K Fischbach… - Neurotoxicity …, 2009 - Springer
Nitric oxide (NO) is an important regulatory molecule for the host defense that plays a
fundamental role in the cardiovascular, immune, and nervous systems. NO is synthesized …

Mitochondrion-specific antioxidants as drug treatments for Alzheimer disease

HH Palacios, BB Yendluri… - CNS & Neurological …, 2011 - ingentaconnect.com
Age-related dementias such as Alzheimer disease (AD) have been linked to vascular
disorders like hypertension, diabetes and atherosclerosis. These risk factors cause …

Oxidative stress induced mitochondrial failure and vascular hypoperfusion as a key initiator for the development of Alzheimer disease

G Aliev, HH Palacios, E Gasimov, ME Obrenovich… - Pharmaceuticals, 2010 - mdpi.com
Mitochondrial dysfunction may be a principal underlying event in aging, including age-
associated brain degeneration. Mitochondria provide energy for basic metabolic processes …

[PDF][PDF] Regenerative potential of dental pulp mesenchymal stem cells harvested from high caries patient's teeth

R Rajendran, S Gopal, H Masood, P Vivek… - Journal of stem …, 2013 - academia.edu
Dental pulp are known to contains stem cells or dentinogenic progenitors that are
responsible for dentin repair. Dental pulp Stem cells from Human Exfoliated Deciduous teeth …

[PDF][PDF] Mitochondria specific antioxidants and their derivatives in the context of the drug development for neurodegeneration and cancer

G Aliev, HH Palacios, P Cacabelos, R Cacabelos… - Drug Des, 2013 - academia.edu
Neurodegeneration and cancer are fast becoming the leading causes of age-associated
disability, dementia and ultimately death worldwide. Although oxidative stress has been …

[PDF][PDF] The three-vessel occlusion as a model of vascular dementia–oxidative stress and mitochondrial failure as an indicator of brain hypoperfusion

G Aliev, J Horecký, O Vančová, GM Ashraf… - Systems Biology of …, 2014 - academia.edu
Brain energy disorders and oxidative stress due to chronic hypoperfusion are considered to
be major risk factors in the pathogenesis of dementia. The aim of our study was to evaluate …

Cardiovascular drugs and triazole based kinase inhibitors as a new strategies for the treatment of Alzheimer disease

AA Ustyugov, GM Aliev - Russian Chemical Bulletin, 2016 - Springer
Atherosclerosis and stroke (including cerebrovascular atheroand arteriosclerosis with
neurological consequences such as Alzheimer disease (AD)) are two leading causes of …

The mobilization of autologous bone marrow stem cells in the treatment of heart failure with Chinese medicine

K Yao, L Zhang, J Wang - Chinese journal of integrative medicine, 2011 - Springer
Heart failure (HF) is a severe heart disease. The use of autologous bone marrow stem cells
(BMCs) mobilization in the treatment of HF has been a hot topic to research both in Western …