From nano to micro to macro: Electrospun hierarchically structured polymeric fibers for biomedical applications

G Yang, X Li, Y He, J Ma, G Ni, S Zhou - Progress in Polymer Science, 2018 - Elsevier
Hierarchically structured polymer fibers encompassing 1-D, 2-D, and 3-D structures with at
least one dimension nano-to micro-meters in size have recently received an increasing …

Cell-matrix mechanical interaction in electrospun polymeric scaffolds for tissue engineering: Implications for scaffold design and performance

KM Kennedy, A Bhaw-Luximon, D Jhurry - Acta biomaterialia, 2017 - Elsevier
Engineered scaffolds produced by electrospinning of biodegradable polymers offer a 3D,
nanofibrous environment with controllable structural, chemical, and mechanical properties …

Antibacterial activity of honey/chitosan nanofibers loaded with capsaicin and gold nanoparticles for wound dressing

S Al-Musawi, S Albukhaty, H Al-Karagoly… - Molecules, 2020 - mdpi.com
This paper describes the preparation, characterization, and evaluation of honey/
tripolyphosphate (TPP)/chitosan (HTCs) nanofibers loaded with capsaicin derived from the …

Emerging roles of electrospun nanofibers in cancer research

S Chen, SK Boda, SK Batra, X Li… - Advanced healthcare …, 2018 - Wiley Online Library
This article reviews the recent progress of electrospun nanofibers in cancer research. It
begins with a brief introduction to the emerging potential of electrospun nanofibers in cancer …

Collagen remodeling along cancer progression providing a novel opportunity for cancer diagnosis and treatment

K Song, Z Yu, X Zu, G Li, Z Hu, Y Xue - International Journal of Molecular …, 2022 - mdpi.com
The extracellular matrix (ECM) is a significant factor in cancer progression. Collagens, as the
main component of the ECM, are greatly remodeled alongside cancer development. More …

Extracellular matrix remodeling and stiffening modulate tumor phenotype and treatment response

JL Leight, AP Drain, VM Weaver - Annual Review of Cancer …, 2017 - annualreviews.org
Solid tumors are characterized by a remodeled and stiffened extracellular matrix. The
extracellular matrix is not a passive by-product of the tumor, but actively compromises tissue …

New plasma-assisted polymerization/activation route leading to a high density primary amine silanization of PCL/PLGA nanofibers for biomedical applications

S Aliakbarshirazi, R Ghobeira, T Egghe… - Applied Surface …, 2023 - Elsevier
Surface modification of hydrophobic nanofibers (NFs) to introduce cell-interactive chemical
functionalities remains a challenge in biomedical applications. This study presents a novel …

Promoting cell migration and neurite extension along uniaxially aligned nanofibers with biomacromolecular particles in a density gradient

J Xue, T Wu, J Qiu, S Rutledge… - Advanced functional …, 2020 - Wiley Online Library
A simple method based upon masked electrospray is reported for directly generating both
unidirectional and bidirectional density gradients of biomacromolecular particles on …

Influence of microenvironment topography and stiffness on the mechanics and motility of normal and cancer renal cells

C Rianna, M Radmacher - Nanoscale, 2017 - pubs.rsc.org
The tumor microenvironment highly influences cancer cell modes and dynamics, above all
during invasive and metastatic processes. When aiming at studying cancer cell behavior in …

PDAC-on-chip for in vitro modeling of stromal and pancreatic cancer cell crosstalk

V Sgarminato, SL Marasso, M Cocuzza… - Biomaterials …, 2023 - pubs.rsc.org
Pancreatic ductal adenocarcinoma (PDAC) mainly develops in the head of the pancreas,
within the acino-ductal unit composed of acinar and ductal cells surrounded by pancreatic …