Abstract Purpose of Review Diabetic peripheral neuropathy eventually affects nearly 50% of
adults with diabetes during their lifetime and is associated with substantial morbidity …

The American Diabetes Association (ADA)“Standards of Medical Care in Diabetes” includes
the ADA's current clinical practice recommendations and is intended to provide the …

Objective The objective of this clinical practice guideline is to provide updated and new
evidence-based recommendations for the comprehensive care of persons with diabetes …

The American Diabetes Association and the European Association for the Study of Diabetes
convened a panel to update the prior position statements, published in 2012 and 2015, on …

Objective To update the 2011 American Academy of Neurology (AAN) guideline on the
treatment of painful diabetic neuropathy (PDN) with a focus on topical and oral medications …

Importance Primary care clinicians find managing chronic pain challenging. Evidence of
long-term efficacy of opioids for chronic pain is limited. Opioid use is associated with serious …

Neuropathic pain is a frequent condition caused by a lesion or disease of the central or
peripheral somatosensory nervous system. A frequent cause of peripheral neuropathic pain …

Peripheral neuropathy is one of the most common complications of both type 1 and type 2
diabetes. Up to half of patients with diabetes develop neuropathy during the course of their …

Diabetes mellitus is a complex, chronic illness requiring continuous medical care with
multifactorial risk reduction strategies beyond glycemic control. Ongoing patient self …

Importance Many patients with diabetic peripheral neuropathy experience chronic pain and
inadequate relief despite best available medical treatments. Objective To determine whether …