Immunomodulatory biomaterials for tissue repair

R Whitaker, B Hernaez-Estrada, RM Hernandez… - Chemical …, 2021‏ - ACS Publications
All implanted biomaterials are targets of the host's immune system. While the host
inflammatory response was once considered a detrimental force to be blunted or avoided, in …

Advanced drug delivery systems and artificial skin grafts for skin wound healing

HS Kim, X Sun, JH Lee, HW Kim, X Fu… - Advanced drug delivery …, 2019‏ - Elsevier
Cutaneous injuries, especially chronic wounds, burns, and skin wound infection, require
painstakingly long-term treatment with an immense financial burden to healthcare systems …

Obesity and prostate cancer—microenvironmental roles of adipose tissue

A Saha, MG Kolonin, J DiGiovanni - Nature Reviews Urology, 2023‏ - nature.com
Obesity is known to have important roles in driving prostate cancer aggressiveness and
increased mortality. Multiple mechanisms have been postulated for these clinical …

Injectable hydrogels with in situ double network formation enhance retention of transplanted stem cells

L Cai, RE Dewi, SC Heilshorn - Advanced functional materials, 2015‏ - Wiley Online Library
Stem cell transplantation via direct injection is a minimally invasive strategy being explored
for treatment of a variety of injuries and diseases. Injectable hydrogels with shear moduli< …

Mesenchymal stem cells and cutaneous wound healing: current evidence and future potential

M Isakson, C De Blacam, D Whelan… - Stem cells …, 2015‏ - Wiley Online Library
Human skin is a remarkable organ that sustains insult and injury throughout life. The ability
of skin to expeditiously repair wounds is paramount to survival. With an aging global …

Tissue engineering and regenerative repair in wound healing

MS Hu, ZN Maan, JC Wu, RC Rennert… - Annals of biomedical …, 2014‏ - Springer
Wound healing is a highly evolved defense mechanism against infection and further injury. It
is a complex process involving multiple cell types and biological pathways. Mammalian …

[HTML][HTML] Adipose-derived stem cells protect skin flaps against ischemia/reperfusion injury via IL-6 expression

CM Pu, CW Liu, CJ Liang, YH Yen, SH Chen… - Journal of Investigative …, 2017‏ - Elsevier
Flap necrosis is the most frequent postoperative complication encountered in reconstructive
surgery. We elucidated whether adipose-derived stem cells (ADSCs) and their derivatives …

Adipose-derived stem cell-based optimization strategies for musculoskeletal regeneration: recent advances and perspectives

C Yuan, W Song, X Jiang, Y Wang, C Li, W Yu… - Stem Cell Research & …, 2024‏ - Springer
Musculoskeletal disorders are the leading causes of physical disabilities worldwide. The
poor self-repair capacity of musculoskeletal tissues and the absence of effective therapies …

Regenerative potential of mesenchymal stromal cells in wound healing: unveiling the influence of normoxic and hypoxic environments

M Mahjoor, A Fakouri, S Farokhi, H Nazari… - Frontiers in Cell and …, 2023‏ - frontiersin.org
The innate and adaptive immune systems rely on the skin for various purposes, serving as
the primary defense against harmful environmental elements. However, skin lesions may …

An antibacterial nanoclay-and chitosan-based quad composite with controlled drug release for infected skin wound healing

W Wei, M Wang, Z Liu, W Zheng, PL Tremblay… - Carbohydrate …, 2024‏ - Elsevier
Microbial infections of surgical sites and other wounds represent a major impediment for
patients. Multifunctional low-cost dressings promoting tissue reparation while preventing …