This paper introduces a new construct, the 'pivotal mental state', which is defined as a hyper-
plastic state aiding rapid and deep learning that can mediate psychological transformation …

Associations between influenza infection and psychosis have been reported since the
eighteenth century, with acute “psychoses of influenza” documented during multiple …

Intriguing findings on genetic and environmental causation suggest a need to reframe the
etiology of mental disorders. Molecular genetics shows that thousands of common and rare …

Schizophrenia is a severe neuropsychiatric disorder with persistence of symptoms
throughout adult life in most of the affected patients. This unfavorable course is associated …

Both the discovery of biomarkers of schizophrenia and the verification of biological
hypotheses of schizophrenia are an essential part of the process of understanding the …

This paper takes a comprehensive look at the latest evidence regarding the significance of
the first 1000 days, and the biological, global, environmental and social factors that influence …

Background Non-alcoholic fatty liver disease (NAFLD) is characterized by hepatic steatosis
in over 5% of the parenchyma in the absence of excessive alcohol consumption. It is more …

Schizophrenia is a complex, chronic mental health disorder whose heterogeneous genetic
and neurobiological background influences early brain development, and whose precise …

Illness staging is widely utilized in several medical disciplines to help predict course or
prognosis, and optimize treatment. Staging models in psychiatry in general, and bipolar …

Schizophrenia and bipolar disorder (BD) are complex and multidimensional disorders with
high heritability rates. The contribution of genetic factors to the etiology of these disorders is …