Simple Summary Nuclear factor erythroid-derived 2-like 2 (encoded by the Nfe2l2 gene;
NRF2) is a transcription factor that regulates a variety of cytoprotective genes, including …

Skin is constantly exposed to environmental insults, including toxic chemicals and oxidative
stress. These insults often provoke perturbation of epidermal homeostasis and lead to …

This study examines the association of the− 617 C> A polymorphism in the Nrf2 gene
(rs6721961) with male infertility in a Turkish population and determines its functional role in …

Objective This study aimed to explore the association of single nucleotide polymorphisms
(SNP) in the matrix metalloproteinase 2 (MMP-2) signaling pathway and the risk of vascular …

Heavy metal-induced toxicity contributes to the progression of various metabolic disorders
and possible mechanisms involved in disease progression are not well established. In this …

The present study is aimed at investigating the association of NFE2L2 gene polymorphisms
with risk and clinical characteristics of acute type A aortic dissection (AAAD) in a Han …

Abstract Background Single-nucleotide polymorphisms (SNPs) of the NF-E2-related factor 2
(NRF2) gene might be associated with several diseases. In the animal models, NRF2 has …

Air pollution is associated with significant adverse health effects. Recent studies support the
idea that inhalation of fine particles can instigate extrapulmonary effects on the …

GABPB1, known as nuclear respiratory factor 2 (Nrf2), activates the mitochondrial genes that
are responsible for antioxidant action and detoxification. Two single nucleotide …

Background: There is a compelling need to emphasize the importance of deepening the
rationale behind functional foods research in molecular biology. Indeed, establishing …