A decade has passed since we published a comprehensive review in this journal
addressing the topic of promoting successful cognitive aging, making this a good time to …

Vascular contributions to cognitive impairment and dementia (VCID) are characterized by
the aging neurovascular unit being confronted with and failing to cope with biological insults …

Sleep dysregulation is a feature of dementia but it remains unclear whether sleep duration
prior to old age is associated with dementia incidence. Using data from 7959 participants of …

Importance Emerging evidence indicates that exposure to fine particulate matter (PM 2.5) air
pollution may increase dementia risk in older adults. Although this evidence suggests …

Background A universal testing and treatment strategy is a potential approach to reduce the
incidence of human immunodeficiency virus (HIV) infection, yet previous trial results are …

Background Social inequalities in mortality persist in high-income countries with universal
health care, and the mechanisms by which these inequalities are generated remain unclear …

Importance Although consumption of ultraprocessed food has been linked to higher risk of
cardiovascular disease, metabolic syndrome, and obesity, little is known about the …

Objective To examine reciprocal relations of loneliness and cognitive function in older
adults. Methods Data were analyzed from 8382 men and women, age 65 and older …

Background: US-based studies have reported that older blacks perform worse than older
whites on cognitive tests and have higher risk of Alzheimer disease dementia (AD). It is …

Abstract Background: The PARAGON-HF (Prospective Comparison of ARNI With ARB
Global Outcomes in HF With Preserved Ejection Fraction) trial tested the efficacy of sacubitril …