SUMMARY Fifty years ago, David Baltimore published a brief conceptual paper delineating
the classification of viruses by the routes of genome expression. The six “Baltimore classes” …

Viruses are ubiquitous parasites of cellular life and the most abundant biological entities on
Earth. It is widely accepted that viruses are polyphyletic, but a consensus scenario for their …

Microbiomes from every environment contain a myriad of uncultivated archaeal and
bacterial viruses, but studying these viruses is hampered by the lack of a universal, scalable …

Microbes drive most ecosystems and are modulated by viruses that impact their lifespan,
gene flow, and metabolic outputs. However, ecosystem-level impacts of viral community …

Viruses with RNA genomes dominate the eukaryotic virome, reaching enormous diversity in
animals and plants. The recent advances of metaviromics prompted us to perform a detailed …

ViPTree is a web server provided through GenomeNet to generate viral proteomic trees for
classification of viruses based on genome-wide similarities. Users can upload viral genomes …

Bacteriophages from the Inoviridae family (inoviruses) are characterized by their unique
morphology, genome content and infection cycle. One of the most striking features of …

Nearly all organisms are hosts to multiple viruses that collectively appear to be the most
abundant biological entities in the biosphere. With recent advances in metagenomics and …

Plasmids and temperate phages are key contributors to bacterial evolution. They are usually
regarded as very distinct. However, some elements, termed phage–plasmids, are known to …

Viruses are the most abundant biological entities on earth and show remarkable diversity of
genome sequences, replication and expression strategies, and virion structures …